Evidence map›Paper›PMID 16581544›Full record

ArticleEnvironmental health perspectives2006

Evolutionary toxicology: population-level effects of chronic contaminant exposure on the marsh frogs (Rana ridibunda) of Azerbaijan.

Cole W Matson, Megan M Lambert, Thomas J McDonald, Robin L Autenrieth, Kirby C Donnelly, Arif Islamzadeh, Dmitri I Politov, John W Bickham

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Cancer in wildlife: patterns of emergence.Nature reviews. Cancer · 2018
    Review
  7. Review
  8. Evolutionary toxicology in an omics world.Evolutionary applications · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The four cornerstones of Evolutionary Toxicology.Ecotoxicology (London, England) · 2011
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Cole W MatsonDepartment of Wildlife and Fisheries Sciences, Texas A&M University, College Station, Texas, USA.
Megan M Lambert
Thomas J McDonald
Robin L Autenrieth
Kirby C Donnelly
Arif Islamzadeh
Dmitri I Politov
John W Bickham
Louisiana Department of Wildlife and Fisheries · USRussian Academy of Sciences · RUSumgayit State University · AZTexas A&M University · US

Funding

WASTE SITE ASSESSMENTP42ES004917 · NIEHS · TEXAS A&M UNIVERSITY SYSTEM · PI SAFE, STEPHEN H. · 1989 to 2009
$10.4M
NIEHS NIH HHS ES 04917NIEHS NIH HHS P42 ES004917
6 · The paper itself

Abstract

We used molecular methods and population genetic analyses to study the effects of chronic contaminant exposure in marsh frogs from Sumgayit, Azerbaijan. Marsh frogs inhabiting wetlands in Sumgayit are exposed to complex mixtures of chemical contaminants, including petroleum products, pesticides, heavy metals, and many other industrial chemicals. Previous results documented elevated estimates of genetic damage in marsh frogs from the two most heavily contaminated sites. Based on mitochondrial DNA (mtDNA) control region sequence data, the Sumgayit region has reduced levels of genetic diversity, likely due to environmental degradation. The Sumgayit region also acts as an ecological sink, with levels of gene flow into the region exceeding gene flow out of the region. Additionally, localized mtDNA heteroplasmy and diversity patterns suggest that one of the most severely contaminated sites in Sumgayit is acting as a source of new mutations resulting from an increased mutation rate. This study provides an integrated method for assessing the cumulative population impacts of chronic contaminant exposure by studying both population genetic and evolutionary effects.

Indexed as

Biological EvolutionAnimalsAzerbaijanBase SequenceDNA, MitochondrialDNA PrimersMutationRana ridibundaWater Pollutants, ChemicalDNA, MitochondrialDNA PrimersWater Pollutants, Chemical

Identifiers

PMID16581544
PMCPMC1440779
OpenAlexW2081500201

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.