ReviewClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2006
Vigilance, alertness, or sustained attention: physiological basis and measurement.
Review in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 277 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
277 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Mental fatigue and brain activation using prolonged task-based fMRI: a systematic review on time-on-task and sequential task paradigms.Experimental brain research · 2026Pooled it
- Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review.BMC psychiatry · 2025Pooled it
- Effects of non-invasive brain stimulation on arousal and alertness among traumatic brain injury patients with disorders of consciousness or persistent vegetative State: a systematic review.Acta neurologica Belgica · 2025Pooled it
- Combining EEG and eye-tracking for cognitive and physiological states monitoring: a systematic review.Frontiers in neuroergonomics · 2025Pooled it
- A systematic review and activation likelihood estimation meta-analysis of fMRI studies on arousing or wake-promoting effects in Buddhist meditation.Frontiers in psychology · 2023Pooled it
- Fatigue Monitoring Through Wearables: A State-of-the-Art Review.Frontiers in physiology · 2021Pooled it
- Applications of EEG indices for the quantification of human cognitive performance: A systematic review and bibliometric analysis.PloS one · 2020Pooled it
- Nocturnal Risk Assessment and Its Association With Anxiety Symptoms.Psychophysiology · 2026Trial
- Impact of a 25-minute nap on cognitive variables and reactive management of disruptive behaviour in trainee secondary school physical education teachers.BMC psychology · 2025Trial
- Can transcutaneous auricular vagus nerve stimulation mitigate vigilance loss? Examining the effects of stimulation at individualized versus constant current intensity.Psychophysiology · 2025Trial
- Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator.BMC medicine · 2024Trial
- Inter-individual variability in neural response to low doses of LSD.Translational psychiatry · 2024Trial
- Impact of repeated morning bright white light exposures on attention in a simulated office environment.Scientific reports · 2023Trial
- Transcutaneous Auricular Vagus Nerve Stimulation Facilitates Cortical Arousal and Alertness.International journal of environmental research and public health · 2023Trial
- Pharmacological Manipulations of Physiological Arousal and Sleep-Like Slow Waves Modulate Sustained Attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Trial
- Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study.Translational psychiatry · 2022Trial
- Impact of chronic sleep restriction on sleep continuity, sleep structure, and neurobehavioral performance.Sleep · 2022Trial
- Changes in vigilance, self rated sleep and state anxiety in military personnel in India following yoga.BMC research notes · 2018Trial
- The relationship between attentional bias and posttraumatic stress symptoms among bereaved parents: a three-year longitudinal study using linear mixed models.European journal of psychotraumatology · 2026Article
- The Sentinel Sleep Theory: Unweaving the biological function of REM sleep.Sleep medicine: X · 2026Article
217 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Vigilance is a term with varied definitions but the most common usage is sustained attention or tonic alertness. This usage of vigilance implies both the degree of arousal on the sleep-wake axis and the level of cognitive performance. There are many interacting neural and neurotransmitter systems that affect vigilance. Most studies of vigilance have relied on states where the sleep-wake state is altered, e.g. drowsiness, sleep-deprivation, and CNS-active drugs, but there are factors ranging from psychophysics to motivation that may impact vigilance. While EEG is the most commonly studied physiologic measure of vigilance, various measures of eye movement and of autonomic nervous system activity have also been used. This review paper discusses the underlying neural basis of vigilance and its assessment using physiologic tools. Since, assessment of vigilance requires assessment of cognitive function this aspect is also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.