ArticleAntiviral research2006
Edible bird's nest extract inhibits influenza virus infection.
Article in Antiviral research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 169 citations in OpenAlex.
- Efficacy of Edible Bird's Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review.Nutrients · 2021Pooled it
- Plant-Derived Food Grade Substances (PDFGS) Active Against Respiratory Viruses: A Systematic Review of Non-clinical Studies.Frontiers in nutrition · 2021Pooled it
- Chemical Heterogeneity Assessment of Authentic Edible Bird's Nests Using Multimodal FTIR Spectroscopy: A Foundation for Future Authentication Strategies.Sensors (Basel, Switzerland) · 2026Article
- Edible bird's nest ameliorates hyperandrogenism and gonadotropin imbalance in a rat model of polycystic ovary syndrome.Frontiers in nutrition · 2026Article
- The Potential of Edible Bird's Nests in Reducing Cardiovascular Disease Risk Factors: A Narrative Review.International journal of molecular sciences · 2025Review
- Uncovering the Antibacterial Potential of a Peptide-Rich Extract of Edible Bird's Nest againstJournal of microbiology and biotechnology · 2024Article
- Edible bird's nest alleviates pneumonia caused by tobacco smoke inhalation through the TNFR1/NF-κB/NLRP3 pathway.Food science & nutrition · 2024Article
- Effects of house-cultivated edible bird's nest on immunoglobulin and cytokine releaseVeterinary world · 2024Article
- Beyond tradition: a novel approach for edible bird nest cleaning and its processing.Veterinary research communications · 2024Review
- The effect of edible bird's nests on the expression of MHC-II and costimulatory molecules of C57BL/6 mouse splenocytes.Biochemistry and biophysics reports · 2023Article
- Recent advances onSynthetic and systems biotechnology · 2023Review
- Using RSM for Optimum of Optimum Production of Peptides from Edible Bird's Nest By-Product and Characterization of Its Antioxidant's Properties.Foods (Basel, Switzerland) · 2022Article
- Edible Bird's Nest as a Potential Cognitive Enhancer.Frontiers in neurology · 2022Review
- Combined enzymatic hydrolysis and herbal extracts fortification to boostChinese herbal medicines · 2021Article
- The Authentication and Grading of Edible Bird's Nest by Metabolite, Nutritional, and Mineral Profiling.Foods (Basel, Switzerland) · 2021Article
- Potential Residual Contaminants in Edible Bird's Nest.Frontiers in pharmacology · 2021Review
- Edible Bird's Nest: Recent Updates and Industry Insights Based On Laboratory Findings.Frontiers in pharmacology · 2021Review
- Edible Bird's Nest: The Functional Values of the Prized Animal-Based Bioproduct From Southeast Asia-A Review.Frontiers in pharmacology · 2021Review
- The Anti-Viral and Anti-Inflammatory Properties of Edible Bird's Nest in Influenza and Coronavirus Infections: From Pre-Clinical to Potential Clinical Application.Frontiers in pharmacology · 2021Review
- Geographical Factor Influences the Metabolite Distribution of House Edible Bird's Nests in Malaysia.Frontiers in nutrition · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Edible bird's nest (EBN) is the nest of the swift that is made from its saliva. Although EBN has been widely used for enhancing immunocompetence, its antiviral efficacy has not been studied in detail. We found that EBN extract could strongly inhibit infection with influenza viruses in a host range-independent manner when it was hydrolyzed with Pancreatin F. Western blotting assay showed that the EBN extract bound to influenza virus. Furthermore, EBN extract could neutralize the infection of MDCK cells with influenza viruses and inhibit hemagglutination of influenza viruses to erythrocytes, but it could not inhibit the activity of influenza virus sialidase. Fluorometric HPLC indicated that the major molecular species of sialic acid in EBN is N-acetylneuraminic acid. The results suggest that EBN is a safe and valid natural source for the prevention of influenza viruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.