Trial reportJournal of psychiatry & neuroscience : JPN2006
Increased positive emotional memory after repetitive transcranial magnetic stimulation over the orbitofrontal cortex.
Trial report in Journal of psychiatry & neuroscience : JPN, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- High-frequency repetitive transcranial magnetic stimulation to the cerebellum and implicit processing of happy facial expressions.Journal of psychiatry & neuroscience : JPN · 2009Trial
- Terahertz photoneuromodulation of lateral orbitofrontal cortex neurons ameliorates stress-induced depression and cognitive impairment.Fundamental research · 2025Article
- Individual- and Connectivity-Based Real-Time fMRI Neurofeedback to Modulate Emotion-Related Brain Responses in Patients with Depression: A Pilot Study.Brain sciences · 2022Article
- Adolescent social isolation induces distinct changes in the medial and lateral OFC-BLA synapse and social and emotional alterations in adult mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Correlation between suicidal ideation and emotional memory in adolescents with depressive disorder.Scientific reports · 2022Article
- Probing fMRI brain connectivity and activity changes during emotion regulation by EEG neurofeedback.Frontiers in human neuroscience · 2022Article
- A Systematic Review of the Effectiveness of Non-Invasive Brain Stimulation Techniques to Reduce Violence Proneness by Interfering in Anger and Irritability.Journal of clinical medicine · 2020Review
- Ventral prefrontal cortex and emotion regulation in aging: A case for utilizing transcranial magnetic stimulation.International journal of geriatric psychiatry · 2019Review
- Animal models to improve our understanding and treatment of suicidal behavior.Translational psychiatry · 2017Review
- Interfering with activity in the dorsomedial prefrontal cortex via TMS affects social impressions updating.Cognitive, affective & behavioral neuroscience · 2016Article
- An electroencephalography network and connectivity analysis for deception in instructed lying tasks.PloS one · 2015Article
- A perfect match: noninvasive brain stimulation and psychotherapy.European archives of psychiatry and clinical neuroscience · 2014Review
- Enhancement of human cognitive performance using transcranial magnetic stimulation (TMS).NeuroImage · 2014Review
- Learning and memory.Handbook of clinical neurology · 2013Review
- The impact of the posterior parietal and dorsolateral prefrontal cortices on the optimization of long-term versus immediate value.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Effects of frontal transcranial direct current stimulation on emotional state and processing in healthy humans.Frontiers in psychiatry · 2012Article
- Diffusion tensor imaging of incentive effects in prospective memory after pediatric traumatic brain injury.Journal of neurotrauma · 2011Article
- The neuroscience of suicidal behaviors: what can we expect from endophenotype strategies?Translational psychiatry · 2011Article
- The cerebellum in emotion regulation: a repetitive transcranial magnetic stimulation study.Cerebellum (London, England) · 2009Article
- An efficient and accurate new method for locating the F3 position for prefrontal TMS applications.Brain stimulation · 2009Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSeveral studies have demonstrated increased left orbitofrontal cortex (OFC) activity during negative and depressed mood. These mood states have also been associated with reduced memory for positive emotional stimuli. The aim of the present study was to investigate whether slow, inhibitory repetitive transcranial magnetic stimulation (rTMS) over the left OFC would improve memory for positive material.
methodsWe carried out a study with a double-blind, within-subjects design, in which 12 healthy volunteers received 20 minutes of slow rTMS over the left OFC, placebo treatment over the left OFC and rTMS over the left dorsolateral portion of the prefrontal cortex. Effects on memory for fearful and happy faces were investigated.
resultsMemory for happy faces was significantly improved after rTMS over the left OFC compared with placebo (t10 = 2.4, p = 0.037).
conclusionsThese findings suggest a role of the OFC in positive emotional memory, which is in accordance with neuroimaging and neuropsychological data. It may be argued that dense projections from the OFC to the limbic emotional circuit are involved in emotional memory and, therefore, play a role in the effects of rTMS that we observed.
Indexed as
Identifiers
16575425PMC1413956What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.