Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2006
Postfatigue potentiation of the paralyzed soleus muscle: evidence for adaptation with long-term electrical stimulation training.
Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Strategies for Rapid Muscle Fatigue Reduction during FES Exercise in Individuals with Spinal Cord Injury: A Systematic Review.PloS one · 2016Pooled it
- Mathematical models of human paralyzed muscle after long-term training.Journal of biomechanics · 2007Trial
- Feedback-controlled stimulation enhances human paralyzed muscle performance.Journal of applied physiology (Bethesda, Md. : 1985) · 2006Trial
- Low-frequency electrically induced exercise after spinal cord injury: Physiologic challenge to skeletal muscle and feasibility for long-term use.The journal of spinal cord medicine · 2024Article
- RNA-seq data of soleus muscle tissue after spinal cord injury under conditions of inactivity and applied exercise.Data in brief · 2020Article
- Hybrid stimulation enhances torque as a function of muscle fusion in human paralyzed and non-paralyzed skeletal muscle.The journal of spinal cord medicine · 2019Article
- Low force contractions induce fatigue consistent with muscle mRNA expression in people with spinal cord injury.Physiological reports · 2014Article
- A minimal dose of electrically induced muscle activity regulates distinct gene signaling pathways in humans with spinal cord injury.PloS one · 2014Article
- Fatigue modulates synchronous but not asynchronous soleus activation during stimulation of paralyzed muscle.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2013Article
- High dose compressive loads attenuate bone mineral loss in humans with spinal cord injury.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Article
- Prior heat stress effects fatigue recovery of the elbow flexor muscles.Muscle & nerve · 2011Article
- Doublet electrical stimulation enhances torque production in people with spinal cord injury.Neurorehabilitation and neural repair · 2011Article
- Enhancing muscle force and femur compressive loads via feedback-controlled stimulation of paralyzed quadriceps in humans.Archives of physical medicine and rehabilitation · 2011Article
- Altered mRNA expression after long-term soleus electrical stimulation training in humans with paralysis.Muscle & nerve · 2011Article
- Reliability and responsiveness of musculoskeletal ultrasound in subjects with and without spinal cord injury.Ultrasound in medicine & biology · 2010Article
- Fatigue and non-fatigue mathematical muscle models during functional electrical stimulation of paralyzed muscle.Biomedical signal processing and control · 2010Article
- Repeated maximal volitional effort contractions in human spinal cord injury: initial torque increases and reduced fatigue.Neurorehabilitation and neural repair · 2009Article
- Identification of a Modified Wiener-Hammerstein System and Its Application in Electrically Stimulated Paralyzed Skeletal Muscle Modeling.Automatica : the journal of IFAC, the International Federation of Automatic Control · 2009Article
- Doublet stimulation protocol to minimize musculoskeletal stress during paralyzed quadriceps muscle testing.Journal of applied physiology (Bethesda, Md. : 1985) · 2008Article
- Dose estimation and surveillance of mechanical loading interventions for bone loss after spinal cord injury.Physical therapy · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Understanding the torque output behavior of paralyzed muscle has important implications for the use of functional neuromuscular electrical stimulation systems. Postfatigue potentiation is an augmentation of peak muscle torque during repetitive activation after a fatigue protocol. The purposes of this study were 1) to quantify postfatigue potentiation in the acutely and chronically paralyzed soleus and 2) to determine the effect of long-term soleus electrical stimulation training on the potentiation characteristics of recently paralyzed soleus muscle. Five subjects with chronic paralysis (>2 yr) demonstrated significant postfatigue potentiation during a repetitive soleus activation protocol that induced low-frequency fatigue. Ten subjects with acute paralysis (<6 mo) demonstrated no torque potentiation in response to repetitive stimulation. Seven of these acute subjects completed 2 yr of home-based isometric soleus electrical stimulation training of one limb (compliance = 83%; 8,300 contractions/wk). With the early implementation of electrically stimulated training, potentiation characteristics of trained soleus muscles were preserved as in the acute postinjury state. In contrast, untrained limbs showed marked postfatigue potentiation at 2 yr after spinal cord injury (SCI). A single acute SCI subject who was followed longitudinally developed potentiation characteristics very similar to the untrained limbs of the training subjects. The results of the present investigation support that postfatigue potentiation is a characteristic of fast-fatigable muscle and can be prevented by timely neuromuscular electrical stimulation training. Potentiation is an important consideration in the design of functional electrical stimulation control systems for people with SCI.
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