Evidence map›Paper›PMID 16572588›Full record

ArticleGene expression2006

Molecular cloning of the m-Golsyn gene and its expression in the mouse brain.

Eishi Funakoshi, Ayako Hamano, Masaki Fukui, Norito Nishiyama, Kiyokazu Ogita, Nobuyoshi Shimizu, Fumiaki Ito

Open access · hybridAbstract read
In one paragraph

Article in Gene expression, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eishi FunakoshiDepartment of Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan. funakos@pharm.setsunan.ac.jp
Ayako Hamano
Masaki Fukui
Norito Nishiyama
Kiyokazu Ogita
Nobuyoshi Shimizu
Fumiaki Ito
Setsunan University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mouse ortholog of the human GOLSYN gene, termed the m-Golsyn gene, was isolated and mapped to the region on mouse chromosome 15B3.2 syntenic with human chromosome 8q23. Three mRNA species (type la, 1b, and type 2) were produced by use of alternative transcription initiation points and alternative splicing events. The type 1 mRNAs were expressed only in the brain, whereas the type 2 was detected in various tissues. m-Golsyn protein was expressed in various tissues including the brain. Immunohistochemical study of m-Golsyn protein showed its prominent expression in the neuronal cells in various regions of the brain and strong expression in the choroid plexus ependymal cells lining the ventricles. m-Golsyn protein was found to be homologous to syntaphilin, a regulator of synaptic vesicle exocytosis. These results indicate that the m-Golsyn protein may play an important role in intracellular protein transport in neuronal cells of the brain.

Indexed as

Gene ExpressionAlternative SplicingAmino Acid SequenceAnimalsBrainCloning, MolecularDNA, ComplementaryExonsHeLa CellsHumansIntracellular Signaling Peptides and ProteinsIntronsMaleMembrane ProteinsMiceMicrotubule-Associated ProteinsDNA, ComplementaryIntracellular Signaling Peptides and ProteinsMembrane ProteinsMicrotubule-Associated ProteinsNerve Tissue ProteinsRNA, MessengerSNPH protein, humanSYBU protein, humanVesicular Transport Proteins

Identifiers

PMID16572588
PMCPMC6032447
OpenAlexW1994529104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.