ArticleJournal of inflammation (London, England)2006
Anti-inflammatory and anti-arthritic effects of Yucca schidigera: a review.
Article in Journal of inflammation (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 167 citations in OpenAlex.
- Rumen Microbiota and Metabolome Reveal the Effects ofAnimals : an open access journal from MDPI · 2026Article
- Applications and Action Mechanisms ofAnimals : an open access journal from MDPI · 2026Review
- A Panoramic Review on the Management of Rheumatoid Arthritis through Herbalism.Current rheumatology reviews · 2025Review
- Effects of Yucca Extract on Nutrient Digestibility, Antioxidant Status, Estrus and Faecal Microorganism in Gilts.Animals : an open access journal from MDPI · 2024Article
- Effects of Dietary Inclusion of a Proprietary Combination ofAnimals : an open access journal from MDPI · 2024Article
- The Effect ofMetabolites · 2024Article
- Nano-platform Strategies of Herbal Components for the Management of Rheumatoid Arthritis: A Review on the Battle for Next-Generation Formulations.Current drug delivery · 2024Review
- The effect of dietary Yucca schidigera extract supplementation on productive performance, egg quality, and gut health in laying hens with Clostridium perfringens and coccidia challenge.Poultry science · 2023Article
- Comparison of the Effects ofAnimals : an open access journal from MDPI · 2023Article
- Improving productivity in rabbits by using some natural feed additives under hot environmental conditions - A review.Animal bioscience · 2023Article
- Effects of Different Levels of Yucca Supplementation on Growth Rates, Metabolic Profiles, Fecal Odor Emissions, and Carcass Traits of Growing Lambs.Animals : an open access journal from MDPI · 2023Article
- Use of Yucca (Plants (Basel, Switzerland) · 2023Article
- Enhancement of protective vaccine-induced antibody titer to swine diseases and growth performance by Amino-Zn, yucca extract, and β-mannanase feed additive in wean-finishing pigs.Frontiers in veterinary science · 2023Article
- Green Nanotechnology ofNanotechnology, science and applications · 2023Article
- Dietary fenugreek seed extract improves dry matter intake, apparent total tract nutrient digestibility, and alters whole blood transcriptome of Holstein dairy heifers.Translational animal science · 2022Article
- Article
- Effects of Supplementing Finishing Goats withAnimals : an open access journal from MDPI · 2022Article
- Neuroprotective Effect ofMolecules (Basel, Switzerland) · 2022Article
- Review
- Elucidation of the Metabolite Profile ofMolecules (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yucca schidigera is a medicinal plant native to Mexico. According to folk medicine, yucca extracts have anti-arthritic and anti-inflammatory effects. The plant contains several physiologically active phytochemicals. It is a rich source of steroidal saponins, and is used commercially as a saponin source. Saponins have diverse biological effects, including anti-protozoal activity. It has been postulated that saponins may have anti-arthritic properties by suppressing intestinal protozoa which may have a role in joint inflammation. Yucca is also a rich source of polyphenolics, including resveratrol and a number of other stilbenes (yuccaols A, B, C, D and E). These phenolics have anti-inflammatory activity. They are inhibitors of the nuclear transcription factor NFkappaB. NFkB stimulates synthesis of inducible nitric oxide synthase (iNOS), which causes formation of the inflammatory agent nitric oxide. Yucca phenolics are also anti-oxidants and free-radical scavengers, which may aid in suppressing reactive oxygen species that stimulate inflammatory responses. Based on these findings, further studies on the anti-arthritic effects of Yucca schidigera are warranted.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.