Evidence map›Paper›PMID 16569885›Full record

ArticleAntimicrobial agents and chemotherapy2006

Prevalence of first-step mutants among levofloxacin-susceptible invasive isolates of Streptococcus pneumoniae in the United States.

Mathias W R Pletz, Ardaman P Shergill, Lesley McGee, Bernard Beall, Cynthia G Whitney, Keith P Klugman, Active Bacterial Core Surveillance Team

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Global fluoroquinolone resistance epidemiology and implictions for clinical use.Interdisciplinary perspectives on infectious diseases · 2012
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mathias W R PletzHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA. Pletz.Mathias@mh-hannover.de
Ardaman P Shergill
Lesley McGee
Bernard Beall
Cynthia G Whitney
Keith P Klugman
Active Bacterial Core Surveillance Team

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By use of a PCR-restriction fragment length polymorphism assay, we screened 496 levofloxacin-susceptible invasive pneumococcal strains (MIC<or=2 mg/liter) for quinolone resistance-determining region mutations known to confer fluoroquinolone resistance. Among those with a levofloxacin MIC of 2 mg/liter, 16.2% of isolates recovered from nursing home residents and 6.4% from non-nursing home residents had first-step mutations.

Indexed as

LevofloxacinMutationAdultAgedAnti-Bacterial AgentsHumansLong-Term CareMicrobial Sensitivity TestsMiddle AgedOfloxacinStreptococcus pneumoniaeAnti-Bacterial AgentsLevofloxacinOfloxacin

Identifiers

PMID16569885
PMCPMC1426940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.