ReviewCurrent rheumatology reports2006
Do antiphospholipid antibodies develop for a purpose?
Review in Current rheumatology reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Regulators and Conductors of Immunity: Natural Immune System in Health and Autoimmunity.International journal of molecular sciences · 2025Review
- Antiphospholipid Antibodies Overlapping in Isolated Neurological Syndrome and Multiple Sclerosis: Neurobiological Insights and Diagnostic Challenges.Frontiers in cellular neuroscience · 2019Article
- Anti-phospholipid Antibodies and Smoking: An Overview.Clinical reviews in allergy & immunology · 2017Review
- Antiphospholipid Antibodies: Their Origin and Development.Antibodies (Basel, Switzerland) · 2016Review
- βAntibodies (Basel, Switzerland) · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a growing body of literature suggesting that antiphospholipid antibodies develop for a purpose, that they play several key roles in the innate immune response, and are only rendered pathologic in susceptible people under adverse intravascular conditions. This paper will review evidence that the autoantibodies associated with the antiphospholipid syndrome develop from natural autoantibodies for purposes that are beneficial to host defense, and are only rendered pathologic as a result of adverse intravascular events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.