Evidence map›Paper›PMID 16569232›Full record

ArticleBMC family practice2006

Serious infections in children: an incidence study in family practice.

Ann Van den Bruel, Stefaan Bartholomeeusen, Bert Aertgeerts, Carla Truyers, Frank Buntinx

Registry-linked trialAbstract read
In one paragraph

Article in BMC family practice, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04074239 (Using Video Transmission for Optimized Telephone Triage of Children With Fever at the Medical Helpline 1813 in Copenhagen, Denmark), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04074239 nacompletednot on this mapstarted 2019, after this paper: background citation

Using Video Transmission for Optimized Telephone Triage of Children With Fever at the Medical Helpline 1813 in Copenhagen, Denmark

TypeinterventionalSponsorEmergency Medical Services, Capital Region, DenmarkRan2019 to 2020Enrolled801ConditionsFever, Telemedicine, Pediatrics, TriageArmsVideo triage
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Article
  10. Aspects of triage for infants: a narrative review.European journal of pediatrics · 2025
    Review
  11. Assessing children who are acutely ill in general practice using the National PEWS and LqSOFA clinical scores: a retrospective cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  12. Article
  13. Article
  14. Observational
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  16. Accuracy of the NICE traffic light system in children presenting to general practice: a retrospective cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ann Van den BruelAcademisch Centrum voor Huisartsgeneeskunde, Katholieke Universiteit Leuven, Leuven, Belgium. ann.vandenbruel@med.kuleuven.be
Stefaan Bartholomeeusen
Bert Aertgeerts
Carla Truyers
Frank Buntinx

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInformation on the incidence of serious infections in children in general practice is scarce. However, estimates on the incidence of disease are important for several reasons, for example to assess the burden of disease or as a basis of diagnostic research. We therefore estimated the incidence of serious infections in general practice in Belgium.

methodsIntego is a morbidity registration network, in which 51 general practitioners continuously register all diagnoses and additional data in their electronic medical records. Serious infections were defined as pneumonia, sepsis, meningitis, pyelonephritis and osteomyelitis. Incidences are calculated for the period of 1998 to 2002, per 1000 patients in the yearly contact group, which is the group of patients that consulted their GP at least once that year, and in the practice population, which is the estimated true population of that practice.

resultsThe incidence of all infectious diseases peaks in children between 0 and 4 years, with 1731 infections per 1000 children per year in the yearly contact group. Incidence drops with increasing age: 972 infections per 1000 children per year in children between 5 and 9 years old, and 732 in children between 10 and 14 years old. The same decline in incidence is observed in the subgroup of serious infections: 21 infections per 1000 children per year in children between 0 and 4 years, 12 in children between 5 and 9 years and 5 in children between 10 and 14 years. The results for the estimated practice population are respectively 17, 9 and 4 serious infections per 1000 children per year.

conclusionIn contrast to the total incidence of acute infections, serious infections are rare, around 1% per year. Children younger than 4 years old have the highest risk for serious infections, and incidences of some infections are different for boys and girls.

Indexed as

Acute DiseaseAdolescentAge DistributionBelgiumChildChild, PreschoolFamily PracticeFemaleHumansIncidenceInfantInfant, NewbornMaleMeningitisOsteomyelitisPediatrics

Identifiers

PMID16569232
PMCPMC1435901

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.