Evidence map›Paper›PMID 16568904›Full record

ReviewCurrent topics in microbiology and immunology2006

Arenavirus diversity and evolution: quasispecies in vivo.

N Sevilla, J C de la Torre

Abstract readReview
In one paragraph

Review in Current topics in microbiology and immunology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. New World Arenavirus Biology.Annual review of virology · 2017
    Review
  8. Arenavirus Quasispecies and Their Biological Implications.Current topics in microbiology and immunology · 2016
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Viral quasispecies evolution.Microbiology and molecular biology reviews : MMBR · 2012
    Review
  14. Article
  15. Article
  16. Arenavirus genetic diversity and its biological implications.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2009
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

N SevillaCentro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain. nsevilla@cbm.uam.es
J C de la Torre

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arenaviruses exist as viral quasispecies due to the high mutation rates of the low-fidelity viral RNA-dependent RNA polymerase (RdRp). This genomic heterogeneity is advantageous to the population, allowing for adaptation to rapidly changing environments that present varying types and degrees of selective pressure. The significant variation in biological properties observed among lymphocytic choriomeningitis virus (LCMV) strains, the prototypic arenavirus, indicates to what extent a quasis-pecies dynamics may play a role in arenavirus adaptability and pathogenesis. Several aspects of arenavirus variability and its contribution to pathogenesis will be discussed.

Indexed as

Evolution, MolecularMutationAnimalsArenavirusGenetic VariationGrowth HormoneLymphocytic choriomeningitis virusMiceReassortant VirusesRecombination, GeneticVirus ReplicationGrowth Hormone

Identifiers

PMID16568904
PMCPMC7120374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.