ArticleIntensive care medicine2006
Avian influenza (H5N1): implications for intensive care.
Article in Intensive care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Hepatic involvement in major respiratory viral infections.Clinical and experimental hepatology · 2025Review
- Selected microwave irradiation effectively inactivates airborne avian influenza A(H5N1) virus.Scientific reports · 2025Article
- Portable UV-C device to treat high flow of infectious aerosols generated during clinical respiratory care.Scientific reports · 2024Article
- Portable UV-C Device to Treat High Flow of Infectious Aerosols Generated during Clinical Respiratory Care.Research square · 2024Article
- Migrant crisis in Europe: implications for intensive care specialists.Intensive care medicine · 2016Article
- A computationally optimized hemagglutinin virus-like particle vaccine elicits broadly reactive antibodies that protect nonhuman primates from H5N1 infection.The Journal of infectious diseases · 2012Article
- A porcine model for initial surge mechanical ventilator assessment and evaluation of two limited-function ventilators.Critical care medicine · 2011Article
- A modified sequential organ failure assessment score for critical care triage.Disaster medicine and public health preparedness · 2010Article
- Oseltamivir in seasonal, avian H5N1 and pandemic 2009 A/H1N1 influenza: pharmacokinetic and pharmacodynamic characteristics.Clinical pharmacokinetics · 2010Review
- [Organization of intensive care in situation of avian flu pandemic].Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2008Review
- Mechanical ventilation in an airborne epidemic.Clinics in chest medicine · 2008Review
- Review
- Pandemic influenza and hospital resources.Emerging infectious diseases · 2007Article
- Clinical review: update of avian influenza A infections in humans.Critical care (London, England) · 2007Review
- Pandemic influenza: implications for preparation and delivery of critical care services.Journal of intensive care medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs influenza A/H5N1 spreads around the globe the risk of an epidemic increases. DISCUSSION: Review of the cases of influenza A/H5N1 reported to date demonstrates that it causes a severe illness, with a high proportion of patients (63%) requiring advanced organ support. Of these approx. 68% develop multiorgan failure, at least 54% develop acute respiratory distress syndrome, and 90% die. Disease progression is rapid, with a median time from presentation to hospital to requirement for advanced organ support of only 2 days.
conclusionThe infectious nature, severity and clinical manifestations of the disease and its potential for pandemic spread have considerable implications for intensive care in terms of infection control, patient management, staff morale and intensive care expansion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.