ArticleMolecular vision2006
Identification of calcium channel alpha1 subunit mRNA expressed in retinal bipolar neurons.
Article in Molecular vision, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Multiple Calcium Channel Types with Unique Expression Patterns Mediate Retinal Signaling at Bipolar Cell Ribbon Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Voltage- and calcium-gated ion channels of neurons in the vertebrate retina.Progress in retinal and eye research · 2019Review
- Dopamine Modulates the Activity of Sensory Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Calcium spike-mediated digital signaling increases glutamate output at the visual threshold of retinal bipolar cells.Journal of neurophysiology · 2015Article
- Differential calcium signaling mediated by voltage-gated calcium channels in rat retinal ganglion cells and their unmyelinated axons.PloS one · 2014Article
- Nitric oxide mediates activity-dependent plasticity of retinal bipolar cell output via S-nitrosylation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Olfactory stimulation selectively modulates the OFF pathway in the retina of zebrafish.Neuron · 2013Article
- Distribution of voltage gated calcium channel β subunits in the mouse retina.Brain research · 2011Article
- Synaptic release at mammalian bipolar cell terminals.Visual neuroscience · 2011Review
- The role of ribbons at sensory synapses.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2009Review
- The molecular architecture of ribbon presynaptic terminals.Molecular neurobiology · 2009Review
- Calcium-dependent inactivation of calcium channels in cochlear hair cells of the chicken.The Journal of physiology · 2007Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposeGlutamate release from goldfish bipolar cell terminals is driven by Ca2+ influx through L-type calcium channels that exhibit several uncommon features, including rapid kinetics of activation and deactivation, slow inactivation, and activation at an unusually negative voltage range for L-type channels. The purpose of this study was to establish the molecular identities of the alpha1 subunits responsible for these distinctive properties.
methodsTranscripts for calcium channel alpha1 subunits expressed in individual goldfish ON-type bipolar cells were identified using single-cell reverse transcriptase polymerase chain reaction (RT-PCR). After cloning the goldfish homologs of the zebrafish and mammalian subunits, we designed sets of nested primers that are specific for Cav1.3a, and Cav1.3b L-type calcium channels.
resultsLarge-terminal, ON-type bipolar cells express transcripts of Cav1.3a and/or Cav1.3b.
conclusionsThe endogenous expression of only one or both subunits in a single cell raises the possibility of functionally distinct classes of bipolar cells that differ in calcium current properties.
Indexed as
Identifiers
16568031PMC1563498W1801771985What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.