ArticleThe Journal of cell biology2006
Controversy fuels trafficking of GPI-anchored proteins.
Article in The Journal of cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- The importance of side branches of glycosylphosphatidylinositol anchors: a molecular dynamics perspective.Glycobiology · 2022Article
- Zwitterionic Character and Lipid Composition Determine the Behaviour of Glycosylphosphatidylinositol Fragments in Monolayers.Chemphyschem : a European journal of chemical physics and physical chemistry · 2021Article
- Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei.Traffic (Copenhagen, Denmark) · 2018Article
- Sphingomyelin is sorted at the trans Golgi network into a distinct class of secretory vesicle.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Proteomic identification of mammalian cell surface derived glycosylphosphatidylinositol-anchored proteins through selective glycan enrichment.Proteomics · 2014Article
- 3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers.Biophysical journal · 2012Article
- Structural features affecting trafficking, processing, and secretion of Trypanosoma cruzi mucins.The Journal of biological chemistry · 2012Article
- Lipid-modified morphogens: functions of fats.Current opinion in genetics & development · 2009Review
- Developmentally regulated sphingolipid synthesis in African trypanosomes.Molecular microbiology · 2008Article
- Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent.American journal of physiology. Renal physiology · 2008Article
- Molecular dissection of the structural machinery underlying the tissue-invasive activity of membrane type-1 matrix metalloproteinase.Molecular biology of the cell · 2008Article
- The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins.Biochemistry · 2008Review
- A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Par1b promotes hepatic-type lumen polarity in Madin Darby canine kidney cells via myosin II- and E-cadherin-dependent signaling.Molecular biology of the cell · 2007Article
- De novo sphingolipid synthesis is essential for viability, but not for transport of glycosylphosphatidylinositol-anchored proteins, in African trypanosomes.Eukaryotic cell · 2007Article
- PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.Molecular biology of the cell · 2006Article
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2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The model that glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) take a direct transport route to the apical membrane of epithelial cells has recently been challenged. In this issue, Paladino et al. (p. 1023) and Hua et al. (p. 1035) show that the original view nevertheless holds. This closes a chapter in the winding story of GPI-AP trafficking but opens another phase, as the controversy has stimulated the development of new methodology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.