ArticleFEBS letters2006
Spatially dependent activation of the patterning protease, Easter.
Article in FEBS letters, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Reconstitution of Torso signaling in cultured cells suggests a role for both Trunk and Torso-like in receptor activation.Development (Cambridge, England) · 2017Article
- A ventrally localized protease in the Drosophila egg controls embryo dorsoventral polarity.Current biology : CB · 2012Article
- Molecular mechanisms of EGF signaling-dependent regulation of pipe, a gene crucial for dorsoventral axis formation in Drosophila.Development genes and evolution · 2012Article
- Activation of Snake in a serine protease cascade that defines the dorsoventral axis is atypical and pipe-independent in Drosophila embryos.FEBS letters · 2010Article
- Pipe-dependent ventral processing of Easter by Snake is the defining step in Drosophila embryo DV axis formation.Current biology : CB · 2010Article
- Morphogen gradient formation.Cold Spring Harbor perspectives in biology · 2009Review
- Mutagenesis of the cysteine-rich clip domain in the Drosophila patterning protease, Snake.Archives of biochemistry and biophysics · 2008Article
- Maternal control of the Drosophila dorsal-ventral body axis.Wiley interdisciplinary reviews. Developmental biologyReview
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The dorsoventral axis of the Drosophila embryo is established by the activating cleavage of a signaling ligand by a serine protease, Easter, only on the ventral side of the embryo. Easter is the final protease in a serine protease cascade in which initial reaction steps appear not to be ventrally restricted, but where Easter activity is promoted ventrally through the action of a spatial cue at an unknown step in the pathway. Here, biochemical studies demonstrate that this spatial control occurs at or above the level of Easter zymogen activation, rather than through direct promotion of Easter's catalytic activity against the signaling ligand.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.