ArticlePLoS genetics2006
Control of daily transcript oscillations in Drosophila by light and the circadian clock.
Article in PLoS genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
77 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Guidelines for Genome-Scale Analysis of Biological Rhythms.Journal of biological rhythms · 2017Guideline
- Meta-analysis of Drosophila circadian microarray studies identifies a novel set of rhythmically expressed genes.PLoS computational biology · 2007Pooled it
- Increased Glycine-N-methyltransferase expression disrupts light-dependent gene expression rhythms in the Drosophila eye.Journal of cell science · 2026Article
- Broad Epigenetic Shifts in the Aging Drosophila Retina Contribute to Its Altered Diurnal Rhythmic Transcriptome.Aging cell · 2026Article
- The Role of Pigments in Light Color Variation of the FireflyEcology and evolution · 2025Article
- Thermoregulated transcriptomics: the molecular basis and biological significance of temperature-dependent alternative splicing.The Biochemical journal · 2024Review
- Analysis of lettuce transcriptome reveals the mechanism of different light/dark cycle in promoting the growth and quality.Frontiers in plant science · 2024Article
- Sleep: An Essential and Understudied Process in the Biology of Blood-Feeding Arthropods.Integrative and comparative biology · 2023Review
- Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster.Nature communications · 2022Article
- Responses of butter leaf lettuce to mixed red and blue light with extended light/dark cycle period.Scientific reports · 2022Article
- Natural alleles of the clock geneFrontiers in physiology · 2022Article
- Circadian regulation of night feeding and daytime detoxification in a formidable Asian pest Spodoptera litura.Communications biology · 2021Article
- A transcriptomic taxonomy ofeLife · 2021Article
- Extensive tissue-specific expression variation and novel regulators underlying circadian behavior.Science advances · 2021Article
- Light Stimuli and Circadian Clock Affect Neural Development inFrontiers in cell and developmental biology · 2021Article
- Methods detecting rhythmic gene expression are biologically relevant only for strong signal.PLoS computational biology · 2020Article
- Molecular mechanisms and physiological importance of circadian rhythms.Nature reviews. Molecular cell biology · 2020Review
- Article
- Genome-wide discovery of the daily transcriptome, DNA regulatory elements and transcription factor occupancy in the monarch butterfly brain.PLoS genetics · 2019Article
- Daily Variations in the Expression of Genes Related to Insecticide Resistance in the Chagas Disease VectorThe American journal of tropical medicine and hygiene · 2019Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The transcriptional circuits of circadian clocks control physiological and behavioral rhythms. Light may affect such overt rhythms in two ways: (1) by entraining the clock circuits and (2) via clock-independent molecular pathways. In this study we examine the relationship between autonomous transcript oscillations and light-driven transcript responses. Transcript profiles of wild-type and arrhythmic mutant Drosophila were recorded both in the presence of an environmental photocycle and in constant darkness. Systematic autonomous oscillations in the 12- to 48-h period range were detectable only in wild-type flies and occurred preferentially at the circadian period length. However, an extensive program of light-driven expression was confirmed in arrhythmic mutant flies. Many light-responsive transcripts are preferentially expressed in the compound eyes and the phospholipase C component of phototransduction, NORPA (no receptor potential), is required for their light-dependent regulation. Although there is evidence for the existence of multiple molecular clock circuits in cyanobacteria, protists, plants, and fungi, Drosophila appears to possess only one such system. The sustained photic expression responses identified here are partially coupled to the circadian clock and may reflect a mechanism for flies to modulate functions such as visual sensitivity and synaptic transmission in response to seasonal changes in photoperiod.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.