ArticleOsteoarthritis and cartilage2006
Expression of superficial zone protein in mandibular condyle cartilage.
Article in Osteoarthritis and cartilage, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 41 citations in OpenAlex.
- Dual-energy computed tomography collagen density mapping of the temporomandibular disc.BMC medical imaging · 2025Article
- The Temporomandibular Joint and the Human Body: A New Perspective on Cross Talk.Dentistry journal · 2024Review
- High-Frequency Near-Infrared Diode Laser Irradiation Attenuates IL-1β-Induced Expression of Inflammatory Cytokines and Matrix Metalloproteinases in Human Primary Chondrocytes.Journal of clinical medicine · 2020Article
- The effects on the mandibular condyle of Botox injection into the masseter are not transient.American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2019Article
- Expression of lubricin in rat posterior mandibular condylar cartilage following functional mandibular forward repositioning.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2019Article
- Activation of α2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint.Scientific reports · 2016Article
- Progenitor Cells of the Mandibular Condylar Cartilage.Current molecular biology reports · 2015Article
- Article
- Isolation and characterization of murine mandibular condylar cartilage cell populations.Cells, tissues, organs · 2012Article
- Murine TMJ loading causes increased proliferation and chondrocyte maturation.Journal of dental research · 2011Article
- Altered functional loading causes differential effects in the subchondral bone and condylar cartilage in the temporomandibular joint from young mice.Osteoarthritis and cartilage · 2009Article
- TMJ disorders: future innovations in diagnostics and therapeutics.Journal of dental education · 2008Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveSuperficial zone protein (SZP) has been shown to function in the boundary lubrication of articular cartilages of the extremities. However, the expression of SZP has not been clarified in mandibular cartilage which is a tissue that includes a thick fibrous layer on the surface. This study was conducted to clarify the distribution of SZP on the mandibular condyle and the regulatory effects of humoral factors on the expression in both explants and fibroblasts derived from mandibular condyle.
methodsThe distribution of SZP was determined in bovine mandibular condyle cartilage, and the effects of interleukin-1beta (IL-1beta) and transforming growth factor-beta (TGF-beta) on SZP expression were examined in condyle explants and fibroblasts derived from the fibrous zone of condyle cartilage.
resultsSZP was highly distributed in the superficial zone of intact condyle cartilage. The SZP expression was up-regulated by TGF-beta in both explants and cultured fibroblasts, whereas the expression was slightly down-regulated by IL-1beta. A significant increase in accumulation of SZP protein was also observed in the culture medium of the fibroblasts treated with TGF-beta.
conclusionsThese results suggest that SZP plays an important role in boundary lubrication of mandible condylar cartilage, is synthesized locally within the condyle itself, and exhibits differential regulation by cell mediators relevant to mandibular condyle repairing and pathologies.
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