Evidence map›Paper›PMID 16563177›Full record

ReviewCritical care (London, England)2006

Rapid molecular detection of methicillin-resistant Staphylococcus aureus: a cost-effective tool for infection control in critical care?

Marc J Struelens, Olivier Denis

Registry-linked trialOpen access · goldAbstract readCommentReview
In one paragraph

Review in Critical care (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00846105 (Two-Center Intervention Study to Evaluate the Impact of Rapid Molecular Screening on Nosocomial Transmission of Methicillin-Resistant Staphylococcus Aureus), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00846105 nacompletednot on this mapstarted 2009, after this paper: background citation

Two-Center Intervention Study to Evaluate the Impact of Rapid Molecular Screening on Nosocomial Transmission of Methicillin-Resistant Staphylococcus Aureus (MRSA).

TypeinterventionalSponsorErasme University HospitalRan2009 to 2010Enrolled7,400ConditionsMethicillin Resistance, Staphylococcus Aureus, Staphylococcal InfectionArmsRapid MRSA PCR test for screening carriers
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. An exploratory cost-effectiveness analysis of methicillin-resistantAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  2. Article
  3. Article
  4. Laboratory evaluation of the BD MAX MRSA assay.Journal of clinical microbiology · 2014
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marc J StruelensDepartment of Microbiology, Université Libre de Bruxelles-Hopital Erasme, Brussels, Belgium. marc.struelens@ulb.ac.be
Olivier Denis
Erasmus Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Control strategies for methicillin-resistant Staphylococcus aureus (MRSA) in critical care remain debated. Timely detection of MRSA carriers is crucial to an effective isolation policy. In this issue, Harbarth and colleagues report rapid MRSA screening among intensive care unit-admitted patients using a PCR assay. Preemptive isolation for all admissions until screened negative for MRSA was associated with a reduction of intensive care unit-acquired MRSA infections in one of two study units. The data provide preliminary evidence to the effectiveness of a MRSA control strategy combining rapid screening by a molecular method and preventive isolation. Further controlled studies are needed to evaluate the cost-effectiveness of this intervention.

Indexed as

Methicillin ResistanceCritical CareHumansInfection ControlStaphylococcal InfectionsStaphylococcus aureus

Identifiers

PMID16563177
PMCPMC1550907
OpenAlexW1544630404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.