ReviewChromosoma2006
The many facets of SC function during C. elegans meiosis.
Review in Chromosoma, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
41 citing papers in PubMed.
- Active maintenance of meiosis-specific chromosome structures inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Active maintenance of meiosis-specific chromosome structures inbioRxiv : the preprint server for biology · 2025Article
- Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol.Cell reports · 2023Article
- Review
- Systematic analysis of long intergenic non-coding RNAs inRNA biology · 2021Article
- Slx5p-Slx8p Promotes Accurate Chromosome Segregation by Mediating the Degradation of Synaptonemal Complex Components during Meiosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Antioxidant CoQ10 Restores Fertility by Rescuing Bisphenol A-Induced Oxidative DNA Damage in theGenetics · 2020Article
- Assessing effects of germline exposure to environmental toxicants by high-throughput screening in C. elegans.PLoS genetics · 2019Article
- A Role in Apoptosis Regulation for theGenetics · 2018Article
- Meiosis.WormBook : the online review of C. elegans biology · 2017Review
- Article
- Article
- Reproductive toxicity and meiotic dysfunction following exposure to the pesticides Maneb, Diazinon and Fenarimol.Toxicology research · 2015Article
- NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis.PLoS genetics · 2015Article
- The meiotic checkpoint network: step-by-step through meiotic prophase.Cold Spring Harbor perspectives in biology · 2014Review
- Protein phosphatase 4 promotes chromosome pairing and synapsis, and contributes to maintaining crossover competence with increasing age.PLoS genetics · 2014Article
- Conservation and variability of synaptonemal complex proteins in phylogenesis of eukaryotes.International journal of evolutionary biology · 2014Article
- Meiotic double-strand breaks uncover and protect against mitotic errors in the C. elegans germline.Current biology : CB · 2013Article
- Pro-crossover factors regulate damage-dependent apoptosis in the Caenorhabditis elegans germ line.Cell death and differentiation · 2013Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Sexually reproducing organisms rely on meiosis for the formation of haploid gametes. This is achieved through two consecutive rounds of cell division (meiosis I and II) after one round of DNA replication. During the meiotic divisions, chromosomes face several challenges to ultimately ensure proper chromosome segregation. Unique events unfold during meiosis I to overcome these challenges. Homologous chromosomes pair, synapse, and recombine. A remarkable feature throughout this process is the formation of an evolutionarily conserved tripartite proteinaceous structure known as the synaptonemal complex (SC). It is comprised of two lateral elements, assembled along each axis of a pair of homologous chromosomes, and a central region consisting of transverse filaments bridging the gap between lateral elements. While the presence of the SC during meiosis has been appreciated now for 50 years (Moses, Biophys Biochem Cytol 2:215-218, 1956; Fawcett, J Biophys Biochem Cytol 2:403-406, 1956), its role(s) remain a matter of intense investigation. This review concentrates on studies performed in Caenorhabditis elegans, a powerful system for investigating meiosis. Studies in this organism are contributing to the unraveling of the various processes leading to the formation of the SC and the various facets of the functions it exerts throughout meiosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.