Evidence map›Paper›PMID 16554851›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2006

Hemodynamic disturbances associated with endovascular embolization in newborn infants with vein of Galen malformation.

F Y Wong, P J Mitchell, B M Tress, P A Dargaville, P M Loughnan

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Vein of Galen aneurysmal malformations: retrospective evaluation of endovascular treatment outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  3. Review
  4. Pulmonary hypertension associated with vein of Galen malformation. Fetal cardiac hemodynamic findings and physiological considerations.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Hemodynamic disturbances associated with endovascular embolization.Journal of perinatology : official journal of the California Perinatal Association · 2006
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

F Y WongDepartment of Neonatology, The Royal Children's Hospital, Melbourne, Australia. flora.wong@med.monash.edu.au
P J Mitchell
B M Tress
P A Dargaville
P M Loughnan
Royal Children's Hospital · AUThe Royal Melbourne Hospital · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine hemodynamic changes following endovascular embolization in newborn infants with vein of Galen malformation and severe cardiac failure in the first week of life. STUDY

designOver a recent 5-year period, nine such infants were identified. In seven of these infants, changes in arterial blood pressure were analyzed in relation to the timing of embolization procedures.

resultsA significant increase in arterial blood pressure was noted after most embolizations. In two infants, this systemic hypertension was severe and treated using intravenous antihypertensive drugs. Both infants subsequently developed complete infarction of both cerebral hemispheres with sparing of the brainstem and cerebellum. Mortality in the nine infants was 33%, and 83% of the survivors were neurologically normal or near normal at follow-up.

conclusionThe systemic hypertension observed following endovascular embolizations may provide a protective mechanism to maintain cerebral blood flow after reperfusion injury. Lowering blood pressure in this situation may therefore be detrimental.

Indexed as

Arteriovenous FistulaBlood PressureCerebral InfarctionCerebral VeinsEmbolization, TherapeuticFollow-Up StudiesHeart FailureHumansHypertensionHypoxia-Ischemia, BrainInfant, NewbornIntracranial Arteriovenous MalformationsRetrospective Studies

Identifiers

PMID16554851
OpenAlexW2043176422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.