ArticleThe EMBO journal1991
The role of cyclins in the maturation of Patella vulgata oocytes.
Article in The EMBO journal, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 39 citations in OpenAlex.
- Intracellular Pathways of Holothuroid Oocyte Maturation Induced by the Thioredoxin Trx-REES.Antioxidants (Basel, Switzerland) · 2021Article
- Newly assembled cyclin B-cdc2 kinase is required to suppress DNA replication between meiosis I and meiosis II in starfish oocytes.The EMBO journal · 1996Article
- Oocyte activation and passage through the metaphase/anaphase transition of the meiotic cell cycle is blocked in clams by inhibitors of HMG-CoA reductase activity.The Journal of cell biology · 1995Article
- Localization and quantification of cyclin A and B mRNA during the embryonic development of Patella vulgata.Roux's archives of developmental biology : the official organ of the EDBO · 1995Article
- Onset of transcription in Patella vulgata coincides with cell cycle elongation and expression of tubulin genes.Roux's archives of developmental biology : the official organ of the EDBO · 1995Article
- Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.The EMBO journal · 1994Article
- Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins.The EMBO journal · 1994Article
- A nuclear factor required for specific translation of cyclin B may control the timing of first meiotic cleavage in starfish oocytes.Molecular biology of the cell · 1993Article
- The metaphase II arrest in mouse oocytes is controlled through microtubule-dependent destruction of cyclin B in the presence of CSF.The EMBO journal · 1993Article
- Actin genes expressed during early development ofPatella vulgata.Roux's archives of developmental biology : the official organ of the EDBO · 1993Article
- Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits.Molecular biology of the cell · 1992Article
- Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.Molecular biology of the cell · 1992Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have cloned and sequenced the cDNAs encoding Patella vulgata cyclins A and B. The cDNA clones contain an open reading frame of 426 and 408 amino acids respectively, which present similarity with cyclins from other species. Cyclin A and B RNAs are present as polyadenylated and non-polyadenylated RNA in prophase oocytes and are completely polyadenylated in metaphase I. During the first cleavages after fertilization the level of cyclin A and B mRNAs is high and drops when the free swimming stage is reached. Using p13suc1-Sepharose bead precipitation we demonstrate that cyclin synthesis is triggered during maturation and that inhibition of protein synthesis makes the cyclins disappear rapidly from the metaphase I oocytes, which shift to interphase condition. By microinjecting antisense oligonucleotides into metaphase I oocytes, we demonstrate that in vivo ablation of cyclin A and B messengers together gives the same result, whereas microinjection of only one oligonucleotide does not show any effect.
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