ArticleRadiation and environmental biophysics2006
ROS release and Hsp70 expression after exposure to 1,800 MHz radiofrequency electromagnetic fields in primary human monocytes and lymphocytes.
Article in Radiation and environmental biophysics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 91 citations in OpenAlex.
- 4G mobile phone radiation alters some immunogenic and vascular gene expressions, and gross and microscopic and biochemical parameters in the chick embryo model.Veterinary medicine and science · 2023Article
- Understanding the public voices and researchers speaking into the 5G narrative.Frontiers in public health · 2023Review
- Cardiac Cell Exposure to Electromagnetic Fields: Focus on Oxdative Stress and Apoptosis.Biomedicines · 2022Article
- CT2A Cell Viability Modulated by Electromagnetic Fields at Extremely Low Frequency under No Thermal Effects.International journal of molecular sciences · 2019Article
- Magnetic Fields and Reactive Oxygen Species.International journal of molecular sciences · 2017Review
- PERM Hypothesis: The Fundamental Machinery Able to Elucidate the Role of Xenobiotics and Hormesis in Cell Survival and Homeostasis.International journal of molecular sciences · 2017Review
- Effect of 900 MHz Electromagnetic Radiation on the Induction of ROS in Human Peripheral Blood Mononuclear Cells.Journal of biomedical physics & engineering · 2015Article
- Effects of combined radiofrequency radiation exposure on levels of reactive oxygen species in neuronal cells.Journal of radiation research · 2014Article
- Study of oxidative stress in human lens epithelial cells exposed to 1.8 GHz radiofrequency fields.PloS one · 2013Article
- Effects of radiofrequency radiation on human ferritin: an in vitro enzymun assay.Journal of medical signals and sensors · 2012Article
- Electromagnetic fields, oxidative stress, and neurodegeneration.International journal of cell biology · 2012Article
- Investigations on DNA damage and frequency of micronuclei in occupational exposure to electromagnetic fields (EMFs) emitted from video display terminals (VDTs).Genetics and molecular biology · 2010Article
- Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system.Reproductive biology and endocrinology : RB&E · 2009Review
- Effects of electromagnetic fields exposure on the antioxidant defense system.Journal of microscopy and ultrastructureReview
- Article
- Effect of microwave electromagnetic radiation (UHF EMR) on tumor cell viability in experiment.Doklady. Biochemistry and biophysicsArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study is to investigate if 1,800 MHz radiofrequency electromagnetic fields (RF-EMF) can induce reactive oxygen species (ROS) release and/or changes in heat shock protein 70 (Hsp70) expression in human blood cells, using different exposure and co-exposure conditions. Human umbilical cord blood-derived monocytes and lymphocytes were used to examine ROS release after exposure to continuous wave or different GSM signals (GSM-DTX and GSM-Talk) at 2 W/kg for 30 or 45 min of continuous or intermittent (5 min ON/5 min OFF) exposure. The cells were exposed to incubator conditions, to sham, to RF-EMF, or to chemicals in parallel. Cell stimulation with the phorbol ester phorbol-12-myristate-13-acetate (PMA; 1 microM) was used as positive control for ROS release. To investigate the effects on Hsp70 expression, the human monocytes were exposed to the GSM-DTX signal at 2 W/kg for 45 min, or to heat treatment (42 degrees C) as positive control. ROS production and Hsp70 expression were determined by flow cytometric analysis. The data were compared to sham and/or to control values and the statistical analysis was performed by the Student's t-test (P<0.05). The PMA treatment induced a significant increase in ROS production in human monocytes and lymphocytes when the data were compared to sham or to incubator controls. After continuous or intermittent GSM-DTX signal exposure (2 W/kg), a significantly different ROS production was detected in human monocytes if the data were compared to sham. However, this significant difference appeared due to the lowered value of ROS release during sham exposure. In human lymphocytes, no differences could be detected if data were compared either to sham or to incubator control. The Hsp70 expression level after 0, 1, and 2 h post-exposure to GSM-DTX signal at 2 W/kg for 1 h did not show any differences compared to the incubator or to sham control.
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