Evidence map›Paper›PMID 16552483›Full record

ArticleMycopathologia2006

Phospholipase and proteinase activities of clinical isolates of Candida from immunocompromised patients.

C P Girish Kumar, S Suresh Jothi Kumar, Thangam Menon

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 83 citations in OpenAlex.

  1. Repositioning Antimicrobial Peptides Against WHO-Priority Fungi.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Article
  3. Article
  4. Research square · 2024
    Article
  5. Targeting Virulence Factors ofFoods (Basel, Switzerland) · 2022
    Review
  6. Comparison of proteinase activity, hemolysin production, and adherence ability ofJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. In vitro activities ofCurrent medical mycology · 2020
    Article
  11. Article
  12. Article
  13. Estimation of biofilm, proteinase & phospholipase production of theThe Indian journal of medical research · 2017
    Article
  14. Influence of cancer treatment on the Candida albicans isolated from the oral cavities of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Insights into Candida tropicalis nosocomial infections and virulence factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012
    Review
  20. The Malassezia genus in skin and systemic diseases.Clinical microbiology reviews · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C P Girish KumarDepartment of Microbiology, Dr ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai, 600 113, India.
S Suresh Jothi Kumar
Thangam Menon
University of Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sixty-one isolates of Candida recovered from HIV seropositive and cancer patients were studied for elaboration of putative virulence determinants--phospholipase (PL) and secreted aspartyl proteinase (Sap). Forty two (68.85%) isolates examined were PL producers and 51 (83.6%) were positive for Sap. 57.37% (35/61) isolates produced both enzymes. Enzymatic activity was more pronounced in Candida albicans with 100% PL and 94.1% Sap activity. In contrast, non-C. albicans species demonstrated only 29.6% PL and 70.3% Sap activity, indicating interplay of other virulence determinants in these yeasts in colonization and disease.

Indexed as

Aspartic Acid EndopeptidasesCandida albicansCandidiasisHIV SeropositivityHumansImmunocompromised HostNeoplasmsPhospholipasesVirulenceAspartic Acid EndopeptidasesPhospholipases

Identifiers

PMID16552483
OpenAlexW2053811294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.