ArticlePLoS genetics2006
Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon.
Article in PLoS genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Long-Read cDNA Sequencing Enables a "Gene-Like" Transcript Annotation of Transposable Elements.The Plant cell · 2020Article
- Global DNA cytosine methylation variation in Spartina alterniflora at North Inlet, SC.PloS one · 2018Article
- SDG2-Mediated H3K4me3 Is Crucial for Chromatin Condensation and Mitotic Division during Male Gametogenesis in Arabidopsis.Plant physiology · 2017Article
- Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize.BMC plant biology · 2017Article
- A New Class of SINEs with snRNA Gene-Derived Heads.Genome biology and evolution · 2015Article
- Mechanisms underlying epigenetic regulation in Arabidopsis thaliana.Integrative and comparative biology · 2014Review
- Epigenetics: Beyond Chromatin Modifications and Complex Genetic Regulation.Plant physiology · 2014Review
- Article
- Epigenome-wide inheritance of cytosine methylation variants in a recombinant inbred population.Genome research · 2013Article
- Single-base resolution maps of cultivated and wild rice methylomes and regulatory roles of DNA methylation in plant gene expression.BMC genomics · 2012Article
- Epigenetic and epigenomic variation in Arabidopsis thaliana.Trends in plant science · 2012Review
- Article
- Epigenetic Variation May Compensate for Decreased Genetic Variation with Introductions: A Case Study Using House Sparrows (Passer domesticus) on Two Continents.Genetics research international · 2012Article
- Genetic rearrangements can modify chromatin features at epialleles.PLoS genetics · 2011Article
- Article
- Transgenerational epigenetic inheritance in plants.Biochimica et biophysica acta · 2011Review
- Differential regulation of a MYB transcription factor is correlated with transgenerational epigenetic inheritance of trichome density in Mimulus guttatus.The New phytologist · 2011Article
- Three epigenetic information channels and their different roles in evolution.Journal of evolutionary biology · 2011Article
- Transposable elements and small RNAs contribute to gene expression divergence between Arabidopsis thaliana and Arabidopsis lyrata.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Transgenerational epigenetic inheritance: more questions than answers.Genome research · 2010Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epigenetic variation is a potential source of genomic and phenotypic variation among different individuals in a population, and among different varieties within a species. We used a two-tiered approach to identify naturally occurring epigenetic alleles in the flowering plant Arabidopsis: a primary screen for transcript level polymorphisms among three strains (Col, Cvi, Ler), followed by a secondary screen for epigenetic alleles. Here, we describe the identification of stable, meiotically transmissible epigenetic alleles that correspond to one member of a previously uncharacterized non-LTR retroposon family, which we have designated Sadhu. The pericentromeric At2g10410 element is highly expressed in strain Col, but silenced in Ler and 18 other strains surveyed. Transcription of this locus is inversely correlated with cytosine methylation and both the expression and DNA methylation states map in a Mendelian manner to stable cis-acting variation. The silent Ler allele can be converted by the epigenetic modifier mutation ddm1 to a meiotically stable expressing allele with an identical primary nucleotide sequence, demonstrating that the variation responsible for transcript level polymorphism among Arabidopsis strains is epigenetic. We extended our characterization of the Sadhu family members and show that different elements are subject to both genetic and epigenetic variation in natural populations. These findings support the view that an important component of natural variation in retroelements is epigenetic.
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