ArticleInfection and immunity2006
Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88.
Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- The role of helminths in the development of non-communicable diseases.Frontiers in immunology · 2022Review
- Review
- Highlighting the Relevance of CD8Frontiers in immunology · 2021Review
- Significant heterogeneity in Wolbachia copy number within and between populations of Onchocerca volvulus.Parasites & vectors · 2017Article
- MyD88 contribution to ocular surface homeostasis.PloS one · 2017Article
- Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro.Parasite immunology · 2014Article
- Differential induction of Th2- and Th1-associated responses by filarial antigens and endosymbiotic Wolbachia in a murine model of river blindness.European journal of microbiology & immunology · 2012Article
- Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential.Clinical science (London, England : 1979) · 2011Review
- Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment.Clinical microbiology reviews · 2011Review
- Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissues.PLoS neglected tropical diseases · 2010Article
- Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.The Journal of biological chemistry · 2009Article
- Gamma interferon and interleukin-1 receptor 1 regulate neutrophil recruitment to the corneal stroma in a murine model of Onchocerca volvulus keratitis.Infection and immunity · 2009Article
- Toll-like receptors at the ocular surface.The ocular surface · 2008Review
- Of mice, cattle, and humans: the immunology and treatment of river blindness.PLoS neglected tropical diseases · 2008Review
- Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis.Infection and immunity · 2007Article
- Wolbachia in filarial parasites: targets for filarial infection and disease control.Current infectious disease reports · 2007Article
- Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88.Infection and immunity · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dependent on expression of myeloid differentiation factor 88.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.