ArticleInfection and immunity2006
Genomic comparison of Escherichia coli K1 strains isolated from the cerebrospinal fluid of patients with meningitis.
Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- Genetic distribution, characterization, and function ofiScience · 2024Review
- A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates.EBioMedicine · 2023Article
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- Metabolic and Morphotypic Trade-Offs within the Eco-Evolutionary Dynamics of Escherichia coli.Microbiology spectrum · 2022Article
- Outcomes of implementation of the FilmArray meningoencephalitis panel in a tertiary hospital between 2017 and 2020.PloS one · 2022Observational
- Elevated Levels of Interleukin-27 in Early Life Compromise Protective Immunity in a Mouse Model of Gram-Negative Neonatal Sepsis.Infection and immunity · 2020Article
- Type VI Secretion System in PathogenicFrontiers in microbiology · 2019Review
- Evaluation of Recombinant AttenuatedFrontiers in immunology · 2017Article
- Evaluation of Escherichia coli isolates from healthy chickens to determine their potential risk to poultry and human health.PloS one · 2017Article
- Human Meningitis-Associated Escherichia coli.EcoSal Plus · 2016Review
- Article
- Lethal neonatal meningoencephalitis caused by multi-drug resistant, highly virulent Escherichia coli.Infectious diseases (London, England) · 2016Article
- Characterizing the pathotype of neonatal meningitis causing Escherichia coli (NMEC).BMC microbiology · 2015Article
- Zoonotic potential of Escherichia coli isolates from retail chicken meat products and eggs.Applied and environmental microbiology · 2015Article
- Heat shock proteins IbpA and IbpB are required for NlpI-participated cell division in Escherichia coli.Frontiers in microbiology · 2015Article
- Escherichia coli isolates that carry vat, fyuA, chuA, and yfcV efficiently colonize the urinary tract.Infection and immunity · 2012Article
- NlpI facilitates deposition of C4bp on Escherichia coli by blocking classical complement-mediated killing, which results in high-level bacteremia.Infection and immunity · 2012Article
- Hcp family proteins secreted via the type VI secretion system coordinately regulate Escherichia coli K1 interaction with human brain microvascular endothelial cells.Infection and immunity · 2012Article
- Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10.Journal of bacteriology · 2011Article
- Avian-pathogenic Escherichia coli strains are similar to neonatal meningitis E. coli strains and are able to cause meningitis in the rat model of human disease.Infection and immunity · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Escherichia coli is a major cause of enteric/diarrheal diseases, urinary tract infections, and sepsis. E. coli K1 is the leading gram-negative organism causing neonatal meningitis, but the microbial basis of E. coli K1 meningitis is incompletely understood. Here we employed comparative genomic hybridization to investigate 11 strains of E. coli K1 isolated from the cerebrospinal fluid (CSF) of patients with meningitis. These 11 strains cover the majority of common O serotypes in E. coli K1 isolates from CSF. Our data demonstrated that these 11 strains of E. coli K1 can be categorized into two groups based on their profile for putative virulence factors, lipoproteins, proteases, and outer membrane proteins. Of interest, we showed that some open reading frames (ORFs) encoding the type III secretion system apparatus were found in group 2 strains but not in group 1 strains, while ORFs encoding the general secretory pathway are predominant in group 1 strains. These findings suggest that E. coli K1 strains isolated from CSF can be divided into two groups and these two groups of E. coli K1 may utilize different mechanisms to induce meningitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.