Evidence map›Paper›PMID 16551995›Full record

ReviewAJNR. American journal of neuroradiology2006

Central nervous system extraosseous Ewing sarcoma: radiologic manifestations of this newly defined pathologic entity.

J S Pekala, S Gururangan, J M Provenzale, S Mukundan

Abstract readCase ReportsReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. What's in a name? Intracranial peripheral primitive neuroectodermal tumors and CNS primitive neuroectodermal tumors are not the same.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013
    Pooled it
  2. Diagnosis, treatment, and postoperative follow-up of intracranial Ewing sarcoma (EWS): a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Pediatric primary intracranial Ewing's sarcoma involving cavernous sinus: an untamed evil.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Primary intracranial Ewing sarcoma/ peripheral primitive neuroectodermal tumor, an entity of unacquaintance: a series of 8 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  8. Optimum treatment for primary intracranial Ewing sarcoma.Proceedings (Baylor University. Medical Center) · 2020
    Article
  9. Primary intracranial extraosseous Ewing's sarcoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
  10. Article
  11. Primary intracranial Ewing's sarcoma with unusual features.International journal of clinical and experimental pathology · 2015
    Article
  12. [Shoulder girdle, AC and SC joints].Operative Orthopadie und Traumatologie · 2014
    Article
  13. Dural metastasis of Ewing's sarcoma.Surgical neurology international · 2013
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J S PekalaDepartment of Radiology and The Brain Tumor Center at Duke, Durham, NC, USA.
S Gururangan
J M Provenzale
S Mukundan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although these entities are histologically similar, recent advances in molecular genetics have allowed the distinction of central nervous system extraosseous Ewing sarcoma (CNS-EES) from central primitive neuroectodermal tumors (c-PNET) including medulloblastoma and supratentorial PNET. We present 2 cases of pathologically confirmed CNS-EES. Knowledge of CNS-EES as a distinct entity enables the neuroradiologist to suggest the proper diagnosis and the need for special immuno-histochemical and molecular studies to confirm the diagnosis. Because treatment and prognosis are vastly different, the proper diagnosis of CNS-EES versus c-PNET is critical.

Indexed as

Tomography, X-Ray ComputedBrain NeoplasmsChildFemaleHumansSarcoma, Ewing

Identifiers

PMID16551995
PMCPMC7976978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.