ArticleMicrobial cell factories2006
Applications of cell sorting in biotechnology.
Article in Microbial cell factories, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- Separation of intrinsically magnetic cells using magnetic filters.Separation and purification technology · 2025Article
- Identification and monitoring of cell heterogeneity from plasmid recombination during limonene production.Applied microbiology and biotechnology · 2025Article
- Raman micro-spectroscopy as a tool to study immunometabolism.Biochemical Society transactions · 2024Review
- Dissociation of murine oral mucosal tissues for single cell applications.Journal of immunological methods · 2024Article
- A High-Throughput Microfluidic Cell Sorter Using a Three-Dimensional Coupled Hydrodynamic-Dielectrophoretic Pre-Focusing Module.Micromachines · 2023Article
- Isolation of Targeted Hypothalamic Neurons for Studies of Hormonal, Metabolic, and Electrical Regulation.Journal of visualized experiments : JoVE · 2023Article
- Analysis ofFrontiers in cellular and infection microbiology · 2023Review
- Direct electrification of silicon microfluidics for electric field applications.Microsystems & nanoengineering · 2023Article
- MUON: multimodal omics analysis framework.Genome biology · 2022Article
- A universal approach to gene expression engineering.Synthetic biology (Oxford, England) · 2022Article
- Measurement Techniques to Resolve and Control Population Dynamics of Mixed-Culture Processes.Trends in biotechnology · 2021Review
- Selection of high-producing clones by a relative titer predictive model using image analysis.Annals of translational medicine · 2021Article
- Comparison of bias and resolvability in single-cell and single-transcript methods.Communications biology · 2021Article
- Past, Present, and Future of Affinity-based Cell Separation Technologies.Acta biomaterialia · 2020Review
- Aptamers as Reversible Sorting Ligands for Preparation of Cells in Their Native State.Cell chemical biology · 2020Article
- Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells.Computational and structural biotechnology journal · 2020Article
- Development and characterization of aBiotechnology for biofuels · 2020Article
- Rapid micro-assays for amylolytic activities determination: customization and validation of the tests.Applied microbiology and biotechnology · 2019Article
- Analysis of the immunoglobulin G (IgG) secretion efficiency in recombinant Chinese hamster ovary (CHO) cells by using Citrine-fusion IgG.Cytotechnology · 2019Article
- Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines.Biotechnology journal · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to its unique capability to analyze a large number of single cells for several parameters simultaneously, flow cytometry has changed our understanding of the behavior of cells in culture and of the population dynamics even of clonal populations. The potential of this method for biotechnological research, which is based on populations of living cells, was soon appreciated. Sorting applications, however, are still less frequent than one would expect with regard to their potential. This review highlights important contributions where flow cytometric cell sorting was used for physiological research, protein engineering, cell engineering, specifically emphasizing selection of overproducing cell lines. Finally conclusions are drawn concerning the impact of cell sorting on inverse metabolic engineering and systems biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.