Evidence map›Paper›PMID 16550219›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2006

Immunology and homeopathy. 2. Cells of the immune system and inflammation.

Paolo Bellavite, Anita Conforti, Francesco Pontarollo, Riccardo Ortolani

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  4. Article
  5. Testing homeopathy in mouse emotional response models: pooled data analysis of two series of studies.Evidence-based complementary and alternative medicine : eCAM · 2012
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation.Evidence-based complementary and alternative medicine : eCAM · 2011
    Article
  11. Postconditioning hormesis put in perspective: an overview of experimental and clinical studies.Dose-response : a publication of International Hormesis Society · 2011
    Article
  12. Article
  13. Article
  14. Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2009
    Article
  15. Brief homeopathic pathogenetic experimentation: a unique educational tool in Brazil.Evidence-based complementary and alternative medicine : eCAM · 2009
    Article
  16. Dynamized preparations in cell culture.Evidence-based complementary and alternative medicine : eCAM · 2009
    Article
  17. Immunology and homeopathy. 5. The rationale of the 'Simile'.Evidence-based complementary and alternative medicine : eCAM · 2007
    Article
  18. Improvement of Memory by Means of Ultra-Low Doses of Antibodies to S-100B Antigen.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  19. Immunology and homeopathy. 4. Clinical studies-part 2.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  20. Immunology and homeopathy. 4. Clinical studies-part 1.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paolo BellaviteDepartment of Scienze Morfologico-Biomediche, University of Verona, Italy. paolo.bellavite@univr.it
Anita Conforti
Francesco Pontarollo
Riccardo Ortolani

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we describe the results of some experimental laboratory studies aimed at verifying the efficacy of high dilutions of substances and of homeopathic medicines in models of inflammation and immunity. Studies carried out on basophils, lymphocytes, granulocytes and fibroblasts are reviewed. This approach may help to test under controlled conditions the main principles of homeopathy such as 'similarity' of drug action at the cellular level and the effects of dilution/dynamization on the drug activity. The current situation is that few and rather small groups are working on laboratory models for homeopathy. Regarding the interpretation of data in view of the simile principle, we observe that there are different levels of similarity and that the laboratory data give support to this principle, but have not yet yielded the ultimate answer to the action mechanism of homeopathy. Evidence of the biological activity in vitro of highly diluted-dynamized solutions is slowly accumulating, with some conflicting reports. It is our hope that this review of literature unknown to most people will give an original and useful insight into the 'state-of-the-art' of homeopathy, without final conclusions 'for' or 'against' this modality. This kind of uncertainty may be difficult to accept, but is conceivably the most open-minded position now.

Identifiers

PMID16550219
PMCPMC1375241

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.