Evidence map›Paper›PMID 16547640›Full record

ArticleJournal of molecular evolution2006

Evolution of the "OR37" subfamily of olfactory receptors: a cross-species comparison.

Reiner Hoppe, Thomas D Lambert, Paul B Samollow, Heinz Breer, Joerg Strotmann

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of molecular evolution, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  10. Neural computations with mammalian infochemicals.Journal of chemical ecology · 2008
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Reiner HoppeInstitute of Physiology, University of Hohenheim, Garbenstrasse 30, 70593, Stuttgart, Germany.
Thomas D Lambert
Paul B Samollow
Heinz Breer
Joerg Strotmann
University of Hohenheim · DEMitchell Institute · US

Funding

NCRR NIH HHS RR014214
6 · The paper itself

Abstract

Genes encoding the olfactory receptors of the "OR37" subfamily of the mouse are characterized by special features including a clustered expression pattern, assembly in two distinct gene clusters, and highly conserved putative promoter motifs. Mining the rat and dog databases revealed that these two species possess highly conserved clusters of OR37 genes at two syntenic genomic loci. In a prototherian mammal, the platypus (Ornithorhynchus anatinus), none of the characteristic OR37 genes were found. Examination of a metatherian mammal, the gray short-tailed opossum (Monodelphis domestica) revealed seven canonical OR37 genes, all phylogenetically related to cluster II genes and also organized similar to cluster II of eutherian species. In addition, their 5' upstream regions comprised sequence motifs related to the putative regulatory sequences of cluster II genes. Typical cluster I OR37 genes were identified only in the eutherian mammals examined, including the evolutionary ancient anteater, wherein OR37 genes related to both clusters were present. Together, these results reveal novel information concerning the phylogenetic origin and important evolutionary steps of the mammalian-specific OR37 olfactory receptor family.

Indexed as

Evolution, MolecularGenetic SpeciationGenomeAnimalsBase SequenceDogsMolecular Sequence DataOpossumsPhylogenyPlatypusPromoter Regions, GeneticRatsReceptors, OdorantSequence AlignmentOlfr37 protein, mouseReceptors, Odorant

Identifiers

PMID16547640
OpenAlexW2077096026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.