ArticleGenetics2006
Natural variation in a subtelomeric region of Arabidopsis: implications for the genomic dynamics of a chromosome end.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Asymmetric evolution of satellite DNA on homologous and homeologous chromosomes in allotetraploid Narenga porphyrocoma.BMC plant biology · 2026Article
- Atlas of telomeric repeat diversity in Arabidopsis thaliana.Genome biology · 2024Article
- Telomere and subtelomere high polymorphism might contribute to the specificity of homologous recognition and pairing during meiosis in barley in the context of breeding.BMC genomics · 2023Article
- Telomerase-independent survival leads to a mosaic of complex subtelomere rearrangements inGenome research · 2023Article
- A complex network of interactions governs DNA methylation at telomeric regions.Nucleic acids research · 2022Article
- Architecture and evolution of subtelomeres in the unicellular green alga Chlamydomonas reinhardtii.Nucleic acids research · 2021Article
- Keeping Balance Between Genetic Stability and Plasticity at the Telomere and Subtelomere ofFrontiers in cell and developmental biology · 2021Review
- Telomeres and Subtelomeres Dynamics in the Context of Early Chromosome Interactions During Meiosis and Their Implications in Plant Breeding.Frontiers in plant science · 2021Review
- Sequence analysis of wheat subtelomeres reveals a high polymorphism among homoeologous chromosomes.The plant genome · 2020Article
- Telomere and Subtelomere R-loops and Antigenic Variation in Trypanosomes.Journal of molecular biology · 2020Review
- Nuclear Integrants of Organellar DNA Contribute to Genome Structure and Evolution in Plants.International journal of molecular sciences · 2020Review
- TheFrontiers in genetics · 2020Article
- The Repetitive DNA Composition in the Natural Pesticide ProducerFrontiers in plant science · 2019Article
- Common Bean Subtelomeres Are Hot Spots of Recombination and Favor Resistance Gene Evolution.Frontiers in plant science · 2018Article
- Contrasting evolutionary genome dynamics between domesticated and wild yeasts.Nature genetics · 2017Article
- Novel features of telomere biology revealed by the absence of telomeric DNA methylation.Genome research · 2016Article
- Cytogenetic and Sequence Analyses of Mitochondrial DNA Insertions in Nuclear Chromosomes of Maize.G3 (Bethesda, Md.) · 2015Article
- The Subtelomeric khipu Satellite Repeat from Phaseolus vulgaris: Lessons Learned from the Genome Analysis of the Andean Genotype G19833.Frontiers in plant science · 2013Article
- Distribution of 45S rDNA sites in chromosomes of plants: structural and evolutionary implications.BMC evolutionary biology · 2012Article
- Natural variation in Arabidopsis: from molecular genetics to ecological genomics.Plant physiology · 2012Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated genome dynamics at a chromosome end in the model plant Arabidopsis thaliana through a study of natural variation in 35 wild accessions. We focused on the single-copy subtelomeric region of chromosome 1 north (approximately 3.5 kb), which represents the relatively simple organization of subtelomeric regions in this species. PCR fragment-length variation across the subtelomeric region indicated that the 1.4-kb distal region showed elevated structural variation relative to the centromere-proximal region. Examination of nucleotide sequences from this 1.4-kb region revealed diverse DNA rearrangements, including an inversion, several deletions, and an insertion of a retrotransposon LTR. The structures at the deletion and inversion breakpoints are characteristic of simple deletion-associated nonhomologous end-joining (NHEJ) events. There was strong linkage disequilibrium between the distal subtelomeric region and the proximal telomere, which contains degenerate and variant telomeric repeats. Variation in the proximal telomere was characterized by the expansion and deletion of blocks of repeats. Our sample of accessions documented two independent chromosome-healing events associated with terminal deletions of the subtelomeric region as well as the capture of a scrambled mitochondrial DNA segment in the proximal telomeric array. This natural variation study highlights the variety of genomic events that drive the fluidity of chromosome termini.
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