Trial reportPain2006
Lumbar instrumented fusion compared with cognitive intervention and exercises in patients with chronic back pain after previous surgery for disc herniation: a prospective randomized controlled study.
Trial report in Pain, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06169488 (The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation), which is not on this map. Cited by 82 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial
Who cites it
82 citing papers in PubMed, 10 syntheses or guidelines pooled it, 297 citations in OpenAlex.
- Interventions to enhance work participation in people with chronic pain: A systematic review and meta-analysis including analysis of complex psychological intervention components.British journal of health psychology · 2026Pooled it
- Comparison between spinal fusion vs. nonoperative treatment for lumbar degenerative pathology: a systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Prognostic factors for outcome following lumbar spine fusion surgery: a systematic review and narrative synthesis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Common elective orthopaedic procedures and their clinical effectiveness: umbrella review of level 1 evidence.BMJ (Clinical research ed.) · 2021Pooled it
- Systematic review of management of chronic pain after surgery.The British journal of surgery · 2017Pooled it
- Low back pain (chronic).BMJ clinical evidence · 2010Pooled it
- Total disc replacement surgery for symptomatic degenerative lumbar disc disease: a systematic review of the literature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2010Pooled it
- Behavioural treatment for chronic low-back pain.The Cochrane database of systematic reviews · 2010Pooled it
- [Can failed back surgery be prevented? Psychological risk factors for postoperative pain after back surgery].Der Orthopade · 2008Pooled it
- Evidence-informed management of chronic low back pain with cognitive behavioral therapy.The spine journal : official journal of the North American Spine SocietyPooled it
- Dextrose injections for failed back surgery syndrome: a consecutive case series.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Trial
- Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: a prospective randomized double-blind sham-controlled multi-center study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Trial
- Posterior Lumbar Interbody Fusion with Interspinous Fastener Provides Comparable Clinical Outcome and Fusion Rate to Pedicle Screws.Orthopaedic surgery · 2017Trial
- Addition of TLIF does not improve outcome over standard posterior instrumented fusion. 5-10 years long-term Follow-up: results from a RCT.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017Trial
- Interspinous process stabilization with Rocker via unilateral approach versus X-Stop via bilateral approach for lumbar spinal stenosis: a comparative study.BMC musculoskeletal disorders · 2015Trial
- Minimally invasive decompression versus open laminectomy for central stenosis of the lumbar spine: pragmatic comparative effectiveness study.BMJ (Clinical research ed.) · 2015Trial
- Description and design considerations of a randomized clinical trial investigating the effect of a multidisciplinary cognitive-behavioural intervention for patients undergoing lumbar spinal fusion surgery.BMC musculoskeletal disorders · 2014Trial
- Provocative discography screening improves surgical outcome.Wiener klinische Wochenschrift · 2013Trial
- The effect of timing of rehabilitation on physical performance after lumbar spinal fusion: a randomized clinical study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2013Trial
- Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study.BMC musculoskeletal disorders · 2013Trial
22 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by[Operations].2012
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effectiveness of lumbar fusion for chronic low back pain after surgery for disc herniation has not been evaluated in a randomized controlled trial. The aim of the present study was to compare the effectiveness of lumbar fusion with posterior transpedicular screws and cognitive intervention and exercises. Sixty patients aged 25-60 years with low back pain lasting longer than 1 year after previous surgery for disc herniation were randomly allocated to the two treatment groups. Experienced back surgeons performed transpedicular fusion. Cognitive intervention consisted of a lecture intended to give the patient an understanding that ordinary physical activity would not harm the disc and a recommendation to use the back and bend it. This was reinforced by three daily physical exercise sessions for 3 weeks. The primary outcome measure was the Oswestry Disability Index (ODI). Outcome data were analyzed on an intention-to-treat basis. Ninety-seven percent of the patients, including seven of eight patients who had either not attended treatment (n=5) or changed groups (n=2), completed 1-year follow-up. ODI was significantly improved from 47 to 38 after fusion and from 45 to 32 after cognitive intervention and exercises. The mean difference between treatments after adjustment for gender was -7.3 (95% CI -17.3 to 2.7, p=0.15). The success rate was 50% in the fusion group and 48% in the cognitive intervention/exercise group. For patients with chronic low back pain after previous surgery for disc herniation, lumbar fusion failed to show any benefit over cognitive intervention and exercises.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.