ArticlePlant physiology2006
Recruitment of novel calcium-binding proteins for root nodule symbiosis in Medicago truncatula.
Article in Plant physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 56 citations in OpenAlex.
- Loss of Nod25 function does not affect nitrogen-fixing symbiosis in Medicago truncatula.Plant molecular biology · 2026Article
- Calcium in the Life Cycle of Legume Root Nodules.Indian journal of microbiology · 2023Review
- A signal peptide peptidase is required for ER-symbiosome proximal association and protein secretion.Nature communications · 2023Article
- Expression and Variation of the Genes Involved in Rhizobium Nodulation in Red Clover.Plants (Basel, Switzerland) · 2022Article
- MtEFD and MtEFD2: Two transcription factors with distinct neofunctionalization in symbiotic nodule development.Plant physiology · 2022Article
- Article
- GmbZIP1 negatively regulates ABA-induced inhibition of nodulation by targeting GmENOD40-1 in soybean.BMC plant biology · 2021Article
- Gene Expression in Nitrogen-Fixing Symbiotic Nodule Cells inThe Plant cell · 2020Review
- GmBEHL1, a BES1/BZR1 family protein, negatively regulates soybean nodulation.Scientific reports · 2018Article
- Article
- A proteomic atlas of the legume Medicago truncatula and its nitrogen-fixing endosymbiont Sinorhizobium meliloti.Nature biotechnology · 2016Article
- A Laser Dissection-RNAseq Analysis Highlights the Activation of Cytokinin Pathways by Nod Factors in the Medicago truncatula Root Epidermis.Plant physiology · 2016Article
- Proteomic analysis of the soybean symbiosome identifies new symbiotic proteins.Molecular & cellular proteomics : MCP · 2015Article
- Genome-wide identification of CAMTA gene family members in Medicago truncatula and their expression during root nodule symbiosis and hormone treatments.Frontiers in plant science · 2015Article
- Extreme specificity of NCR gene expression in Medicago truncatula.BMC genomics · 2014Article
- Article
- Characterization of the caleosin gene family in the Triticeae.BMC genomics · 2014Article
- Transport processes of the legume symbiosome membrane.Frontiers in plant science · 2014Article
- Article
- Biochemical characteristics of the Ca2+ pumping ATPase in the peribacteroid membrane from broad bean root nodules.Protoplasma · 2013Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legume rhizobia symbiotic nitrogen (N2) fixation plays a critical role in sustainable nitrogen management in agriculture and in the Earth's nitrogen cycle. Signaling between rhizobia and legumes initiates development of a unique plant organ, the root nodule, where bacteria undergo endocytosis and become surrounded by a plant membrane to form a symbiosome. Between this membrane and the encased bacteria exists a matrix-filled space (the symbiosome space) that is thought to contain a mixture of plant- and bacteria-derived proteins. Maintenance of the symbiosis state requires continuous communication between the plant and bacterial partners. Here, we show in the model legume Medicago truncatula that a novel family of six calmodulin-like proteins (CaMLs), expressed specifically in root nodules, are localized within the symbiosome space. All six nodule-specific CaML genes are clustered in the M. truncatula genome, along with two other nodule-specific genes, nodulin-22 and nodulin-25. Sequence comparisons and phylogenetic analysis suggest that an unequal recombination event occurred between nodulin-25 and a nearby calmodulin, which gave rise to the first CaML, and the gene family evolved by tandem duplication and divergence. The data provide striking evidence for the recruitment of a ubiquitous Ca(2+)-binding gene for symbiotic purposes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.