ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2006
Surgical outcome and prognostic factors of pediatric epilepsy caused by cortical dysplasia.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgery for epilepsy.The Cochrane database of systematic reviews · 2019Pooled it
- Hypometabolic patterns of focal cortical dysplasia in PET-MRI co-registration imaging: a retrospective evaluation in a series of 83 patients.Frontiers in neuroscience · 2023Article
- High density electric source imaging in childhood-onset epilepsy due to focal cortical dysplasia.Clinical neurophysiology practice · 2022Article
- Focal cortical dysplasia imaging discrepancies between MRI and FDG-PET: Unique association with temporal lobe location.Seizure · 2020Article
- 5-Aminolevulinic Acid-Induced Fluorescence in Focal Cortical Dysplasia: Report of 3 Cases.Operative neurosurgery (Hagerstown, Md.) · 2019Article
- An initial cost-effectiveness analysis of intraoperative magnetic resonance imaging (iMRI) in pediatric epilepsy surgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- A longitudinal study of surgical outcome of pharmacoresistant epilepsy caused by focal cortical dysplasia.Journal of neurology · 2016Article
- The Severity of Gliosis in Hippocampal Sclerosis Correlates with Pre-Operative Seizure Burden and Outcome After Temporal Lobectomy.Molecular neurobiology · 2016Article
- Resective surgery for focal cortical dysplasia in children: a comparative analysis of the utility of intraoperative magnetic resonance imaging (iMRI).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Early susceptibility for epileptiform activity in malformed cortex.Epilepsy research · 2014Article
- Focal cortical dysplasia and epilepsy surgery.Journal of epilepsy research · 2013Review
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10 authors.
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Abstract
objectsWe analyzed 30 patients with cortical dysplasia (CD) and epilepsy to evaluate the clinical characteristics and surgical outcome of both epilepsy control and neurocognition. MATERIALS AND
methodsThe mean ages at seizure onset and at the time of the operation were 3.6 years (range, 1 month-12.6 years) and 10.3 years (range, 1.5-18.3 years), respectively. The mean follow-up period was 3.2 years (range, 1-5.3 years). (18)FDG-positron emission tomography was the most sensitive and magnetic resonance imaging was the most specific in localizing the lesion. Developmental/intellectual delay was predominant in the early-onset group (n=18, seizure onset <3 years), with intelligence tending to be normal in the late-onset group (n=12, seizure onset >or=3 years). Mild CD predominated in the late-onset epilepsy group and moderate or severe CD in the early-onset group (p=0.005). The surgical success rate of epilepsy control was 87%. A better outcome was obtained if the lesion was confined to the temporal lobe. School performance was favorable in 43%. The age at seizure onset and preoperative developmental/intellectual delay were the important prognostic factors in school performance as well as the epilepsy control. A total of 77% of patients had relatively good social adaptation. Successful epilepsy control and good school performance were affirmative conditions precedent to social adaptation.
conclusionsDue to the favorable control of epilepsy and its effect on school performance and social adaptation, surgical treatment is strongly recommended for cortical dysplasia and intractable epilepsy.
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