Evidence map›Paper›PMID 16540170›Full record

ArticleMolecular immunology2007

CRP can play both pro-inflammatory and anti-inflammatory roles.

Irving Kushner, Alok Agrawal

Abstract readCommentLetter
In one paragraph

Article in Molecular immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  3. Review
  4. Serum amyloid A levels in patients with liver diseases.World journal of gastroenterology · 2019
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Irving Kushner
Alok Agrawal

Funding

Structure-Function Relationships of C-Reactive ProteinR01HL071233 · NHLBI · EAST TENNESSEE STATE UNIVERSITY · PI AGRAWAL, ALOK · 2002 to 2011
$2.6M
NHLBI NIH HHS R01 HL071233
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

C-Reactive ProteinAnimalsApoptosisCardiovascular DiseasesHumansInflammationRatsC-Reactive Protein

Identifiers

PMID16540170
PMCPMC4100330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.