ArticleVirchows Archiv : an international journal of pathology2006
Pancreatic malignant fibrous histiocytoma, inflammatory myofibroblastic tumor, and inflammatory pseudotumor related to autoimmune pancreatitis: characterization and differential diagnosis.
Article in Virchows Archiv : an international journal of pathology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- Primary Pancreatic Undifferentiated Pleomorphic Sarcoma.ACG case reports journal · 2023Article
- Undifferentiated pleomorphic sarcoma of the pancreas: a rare case report and literature review.World journal of surgical oncology · 2022Review
- A Pancreatic Inflammatory Myofibroblastic Tumor with Spontaneous Remission: A Case Report with a Literature Review.Diagnostics (Basel, Switzerland) · 2019Article
- Spontaneous pancreatic undifferentiated pleomorphic sarcoma in a laboratory rat: A case report.Animal models and experimental medicine · 2019Article
- Benign Tumors and Tumorlike Lesions of the Pancreas.Surgical pathology clinics · 2016Review
- Inflammatory myofibroblastic tumor of salpinx: a very rare case treated with a less aggressive method.Iranian journal of cancer prevention · 2014Article
- Prevalence of autoimmune pancreatitis and other benign disorders in pancreatoduodenectomy for presumed malignancy of the pancreatic head.Digestive diseases and sciences · 2012Article
- Benign inflammatory pseudotumour mimicking extrahepatic bile duct cholangiocarcinoma in an adult man presenting with painless obstructive jaundice.BMJ case reports · 2012Review
- Complete Long-Term Remission of an Inflammatory Pseudotumor under Corticosteroid Therapy.Case reports in oncology · 2011Article
- First case of primary phyllodes tumor of the pancreas: case report and findings of immunohistochemical and ultrastructural studies.Virchows Archiv : an international journal of pathology · 2010Article
- Spontaneous development of a pancreatic exocrine disease in CD28-deficient NOD mice.Journal of immunology (Baltimore, Md. : 1950) · 2008Article
- A case of primary malignant fibrous histiocytoma of the pancreas: CT and MRI findings.World journal of gastroenterology · 2008Article
- Inflammatory Pseudotumor of the Pancreas Mimicking a Pancreatic Neoplasm.Case reports in gastroenterologyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant fibrous histiocytoma (MFH) and inflammatory myofibroblastic tumor (IMT) are uncommon primary non-epithelial cell tumors of the pancreas. In addition, there are inflammatory pseudotumors (IPT) that may arise in the course of autoimmune pancreatitis (AIP). In the English language literature, only 24 cases of IMT and nine cases of MFH in the pancreas have been reported to date. We investigated three individual spindle cell tumors of the pancreas that were identified as MFH, IMT, and IPT, respectively, using immunohistochemical and molecular analysis. Both the MFH and the IMT, but not the IPT, showed nuclear p53 expression and mutations of the p53 gene. The MFH and the IMT also had higher mitotic and Ki-67 (MIB-1) indexes than the IPT. The IPT was found to be a tumor-like case of AIP. Many IgG4-positive plasma cells, which are considered to be a feature of AIP, were found in all three tumors. It is concluded that in this series of spindle cell tumors of the pancreas, apart from immunohistochemical features, the demonstration of p53 mutations may be helpful in distinguishing true neoplastic tumors from pseudotumors such as IPTs arising in the context of AIP.
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