ArticleProceedings of the National Academy of Sciences of the United States of America2006
Strict rules determine arrangements of strands in sandwich proteins.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tandem-repeat lectins: structural and functional insights.Glycobiology · 2024Pooled it
- The 3D Invariant Positioning for Protein Molecules / Molecular Complexes with Matching Subunits.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Amino acid distribution rules predict protein fold: protein grammar for beta-strand sandwich-like structures.Biomolecules · 2015Article
- ASTRO-FOLD 2.0: an Enhanced Framework for Protein Structure Prediction.AIChE journal. American Institute of Chemical Engineers · 2012Article
- β-sheet topology prediction with high precision and recall for β and mixed α/β proteins.PloS one · 2012Article
- Efficient motif finding algorithms for large-alphabet inputs.BMC bioinformatics · 2010Article
- Systematic construction and prediction of the arrangement of the strands of sandwich proteins.Journal of the Royal Society, Interface · 2009Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
From a computer analysis of the spatial organization of the secondary structures of beta-sandwich proteins, we find certain sets of consecutive strands that are connected by hydrogen bonds, which we call "strandons." The analysis of the arrangements of strandons in 491 protein structures that come from 69 different superfamilies reveals strict regularities in the arrangements of strandons and the formation of what we call "canonical supermotifs." Six such supermotifs account for approximately 90% of all observed structures. Simple geometric rules are described that dictate the formation of these supermotifs.
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