ArticleProceedings of the National Academy of Sciences of the United States of America2006
Insights into excited-state and isomerization dynamics of bacteriorhodopsin from ultrafast transient UV absorption.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 69 citations in OpenAlex.
- A Detailed View on the (Re)isomerization Dynamics in Microbial Rhodopsins Using Complementary Near-UV and IR Readouts.Angewandte Chemie (International ed. in English) · 2025Article
- Convergent evolution of animal and microbial rhodopsins.RSC advances · 2023Review
- Exploring the mechanism of olfactory recognition in the initial stage by modeling the emission spectrum of electron transfer.PloS one · 2020Article
- Vibrational coherence transfer in the ultrafast intersystem crossing of a diplatinum complex in solution.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Light-Activated Reversible Imine Isomerization: Towards a Photochromic Protein Switch.Chembiochem : a European journal of chemical biology · 2016Article
- Sub-50-fs photoinduced spin crossover in [Fe(bpy)₃]²⁺.Nature chemistry · 2015Article
- Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.Chemical reviews · 2014Review
- Carotenoid response to retinal excitation and photoisomerization dynamics in xanthorhodopsin.Chemical physics letters · 2011Article
- Aborted double bicycle-pedal isomerization with hydrogen bond breaking is the primary event of bacteriorhodopsin proton pumping.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Control of retinal isomerization in bacteriorhodopsin in the high-intensity regime.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Functional electric field changes in photoactivated proteins revealed by ultrafast Stark spectroscopy of the Trp residues.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Terahertz radiation from bacteriorhodopsin reveals correlated primary electron and proton transfer processes.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Computational photochemistry of retinal proteins.Journal of computer-aided molecular designReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A visible-pump/UV-probe transient absorption is used to characterize the ultrafast dynamics of bacteriorhodopsin with 80-fs time resolution. We identify three spectral components in the 265- to 310-nm region, related to the all-trans retinal, tryptophan (Trp)-86 and the isomerized photoproduct, allowing us to map the dynamics from reactants to products, along with the response of Trp amino acids. The signal of the photoproduct appears with a time delay of approximately 250 fs and is characterized by a steep rise ( approximately 150 fs), followed by additional rise and decay components, with time scales characteristic of the J intermediate. The delayed onset and the steep rise point to an impulsive formation of a transition state on the way to isomerization. We argue that this impulsive formation results from a splitting of a wave packet of torsional modes on the potential surface at the branching between the all-trans and the cis forms. Parallel to these dynamics, the signal caused by Trp response rises in approximately 200 fs, because of the translocation of charge along the conjugate chain, and possible mechanisms are presented, which trigger isomerization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.