Evidence map›Paper›PMID 16532346›Full record

SynthesisPediatric radiology2006

Pathological diagnosis of paediatric tumours from image-guided needle core biopsies: a systematic review.

Neil J Sebire, Derek J Roebuck

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric radiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
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  9. Review
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  16. Article
  17. Paediatric interventional oncology.Cancer imaging : the official publication of the International Cancer Imaging Society · 2010
    Review
  18. Paediatric interventional radiology.Pediatric radiology · 2009
    Review
  19. Review
  20. The role of radiology in paediatric soft tissue sarcomas.Cancer imaging : the official publication of the International Cancer Imaging Society · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Neil J SebireDepartment of Paediatric Histopathology, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK. sebirn@gosh.nhs.uk
Derek J Roebuck
Great Ormond Street Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImage-guided core needle biopsy is widely used in paediatric oncology, but many protocols continue to discourage this practice. No published randomized studies compare image-guided needle biopsy with surgical techniques.

objectiveTo perform a systematic review of the literature on image-guided core needle biopsy in paediatric oncology. MATERIALS AND

methodsSeveral computerized databases were searched using the terms [(needle OR core) AND (biops*[ti]) AND (paediatric OR pediatric OR child OR children OR childhood OR boy OR girl)[ti]] to identify series of more than five cases of needle core biopsy for tumour diagnosis in children. Data from included studies were combined to calculate pooled estimates of adequacy, accuracy and complication rates.

resultsThirteen studies fulfilled the inclusion criteria. Overall biopsy adequacy rate (defined as sufficient to make a diagnosis) was 94% (95% CI 92-96%). The diagnostic accuracy rate in cases with adequate material (defined as achieving the correct specific diagnosis) was 94% (95% CI 92-96%). Complications requiring treatment occurred in 1%.

conclusionsAvailable pooled data suggest that about 95% of image-guided needle core biopsies provide an adequate sample for diagnosis of malignant disease in childhood. In such cases, the pathological diagnosis is correct in about 95%. Complications are rare.

Indexed as

Biopsy, NeedleChildHumansNeoplasmsPediatricsSensitivity and SpecificityTomography, X-Ray ComputedUltrasonography

Identifiers

PMID16532346
OpenAlexW2053271434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.