Evidence map›Paper›PMID 16531524›Full record

ArticleGut2006

Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies.

J D Wood

Registry-linked trialAbstract readComment
In one paragraph

Article in Gut, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00583128 (A Double-Blind, Randomized, Placebo-Controlled Multicenter Study to Assess the Safety and Efficacy of AST-120 in Patients With Non-Constipating Irritable Bowel Syndrome), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00583128 phase2completednot on this mapstarted 2007, after this paper: background citation

A Double-Blind, Randomized, Placebo-Controlled Multicenter Study to Assess the Safety and Efficacy of AST-120 in Patients With Non-Constipating Irritable Bowel Syndrome

TypeinterventionalSponsorOcera TherapeuticsRan2007 to 2010Enrolled117ConditionsIrritable Bowel SyndromeArmsAST-120, Celphere® CP-305
3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Frontiers in physiology · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Food allergy and the gut.Nature reviews. Gastroenterology & hepatology · 2017
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Communication between mast cells and rat submucosal neurons.Pflugers Archiv : European journal of physiology · 2015
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

J D WoodDepartment of Physiology and Cell Biology, The Ohio State University College of Medicine, 304 Hamilton Hall, 1645 Neil Ave, Columbus, Ohio 43210-1218, USA. wood.13@osu.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EnteritisFood HypersensitivityHistamineHumansIleumIntestinal MucosaIntestine, LargeIntestine, SmallIrritable Bowel SyndromeMast CellsReceptors, HistamineReceptors, Histamine H1Receptors, Histamine H2HistamineReceptors, HistamineReceptors, Histamine H1Receptors, Histamine H2

Identifiers

PMID16531524
PMCPMC1856149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.