ReviewDental clinics of North America2006
Gene therapeutics for periodontal regenerative medicine.
Review in Dental clinics of North America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 103 citations in OpenAlex.
- Clinical and radiographic effects of ascorbic acid-augmented platelet-rich fibrin versus platelet-rich fibrin alone in intra-osseous defects of stage-III periodontitis patients: a randomized controlled clinical trial.Clinical oral investigations · 2021Trial
- Article
- Gene Therapy for Regenerative Medicine.Pharmaceutics · 2023Review
- Gene Delivery Therapeutics in the Treatment of Periodontitis and Peri-Implantitis: A State of the Art Review.International journal of molecular sciences · 2019Review
- Stem cells: past, present, and future.Stem cell research & therapy · 2019Review
- Erythropoietin induces the osteogenesis of periodontal mesenchymal stem cells from healthy and periodontitis sources via activation of the p38 MAPK pathway.International journal of molecular medicine · 2018Article
- Engineering Stem Cells for Biomedical Applications.Advanced healthcare materials · 2016Review
- Characterization of a shorter recombinant polypeptide chain of bone morphogenetic protein 2 on osteoblast behaviour.BMC oral health · 2015Article
- Cell- and Gene- Based Therapeutics for Periodontal Regeneration.International journal of preventive medicine · 2015Review
- Clinical Application of Mesenchymal Stem Cells and Novel Supportive Therapies for Oral Bone Regeneration.BioMed research international · 2015Review
- A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects.Current pharmaceutical biotechnology · 2015Article
- Clinical evaluation of autologous platelet rich fibrin in horizontal alveolar bony defects.Journal of clinical and diagnostic research : JCDR · 2014Article
- Dental follicle cells rescue the regenerative capacity of periodontal ligament stem cells in an inflammatory microenvironment.PloS one · 2014Article
- The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor.Biomaterials · 2014Article
- Tissue engineering in periodontal regeneration: A brief review.Dental research journal · 2012Article
- Advanced reconstructive technologies for periodontal tissue repair.Periodontology 2000 · 2012Review
- Gene therapy with growth factors for periodontal tissue engineering--a review.Medicina oral, patologia oral y cirugia bucal · 2012Review
- Current status of low intensity pulsed ultrasound for dental purposes.The open dentistry journal · 2012Article
- Cell- and gene-based therapeutic strategies for periodontal regenerative medicine.Journal of periodontology · 2011Review
- Future Prospects for Periodontal Bioengineering Using Growth Factors.Clinical advances in periodontics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
There has been significant advancement in the field of periodontal tissue engineering over the past decade for the repair of tooth-supporting structures. Although encouraging results for periodontal tissue regeneration have been found in numerous clinical investigations using recombinant growth factors, limitations exist with topical protein delivery. Newer approaches seek to develop methodologies that optimize growth factor targeting to maximize the therapeutic outcome of periodontal regenerative procedures. Genetic approaches in periodontal tissue engineering show early progress in achieving delivery of growth factor genes, such as platelet-derived growth factor or bone morphogenetic protein, to periodontal lesions. Ongoing investigations in ex vivo and in vivo gene transfer to periodontia seek to examine the extent of the potential effects in stimulating periodontal tissue engineering.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.