ReviewCerebellum (London, England)2006
Modulation of synaptic activity in Purkinje neurons by ATP.
Review in Cerebellum (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Cerebellar deep brain stimulation rescues Purkinje cell mitochondrial density in a genetic mouse model of cerebellar ataxia.Brain research bulletin · 2026Article
- Challenges and opportunities of advanced gliomodulation technologies for excitation-inhibition balance of brain networks.Current opinion in biotechnology · 2021Review
- A Functional Signature in the Developing Cerebellum: Evidence From a Preclinical Model of Autism.Frontiers in cell and developmental biology · 2021Article
- Reductions in COQ2 Expression Relate to Reduced ATP Levels in Multiple System Atrophy Brain.Frontiers in neuroscience · 2019Article
- Article
- P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction.Neural plasticity · 2016Review
- P2Y1 receptor activation by photolysis of caged ATP enhances neuronal network activity in the developing olfactory bulb.Purinergic signalling · 2012Article
- Purinergic modulation of granule cells.Cerebellum (London, England) · 2012Review
- NMDA receptor agonists fail to alter release from cerebellar basket cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Purine receptor-mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex.British journal of pharmacology · 2011Article
- The cerebellum, cerebellar disorders, and cerebellar research--two centuries of discoveries.Cerebellum (London, England) · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenosine triphosphate (ATP) is a versatile signalling molecule in the central and peripheral nervous system, where it can be released from both neurons and glial cells. In the cerebellum, ATP is released endogenously from the second postnatal week onwards, and is involved in the up-regulation of spontaneous synaptic input to Purkinje neurons by activation of purinergic P2 receptors. In the cerebellar cortex, ATP presumably acts on presynaptic inhibitory interneurons, which are excited by the activation of both P2X and P2Y receptors. P2 receptors have been reported for Purkinje neurons, where they mediate intracellular Ca(2+) responses. The extracellular concentration of ATP is modulated by its enzymatic degradation by ecto-nucleotidases. Adenosine, which modulates evoked transmitter release, does not influence the spontaneous synaptic activity in Purkinje neurons. Some implications of ATP as a tonically active neuromodulator in the cerebellum are discussed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.