Evidence map›Paper›PMID 16527763›Full record

ReviewCerebellum (London, England)2006

The role of secretin in the cerebellum.

Wing-Ho Yung, Ying-Shing Chan, Billy K C Chow, Jian-Jun Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cerebellum (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Neuropeptides and Their Roles in the Cerebellum.International journal of molecular sciences · 2024
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Secretin: Should we revisit its metabolic outcomes?Journal of endocrinological investigation · 2010
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Wing-Ho YungDepartment of Physiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong. whyung@cuhk.edu.hk
Ying-Shing Chan
Billy K C Chow
Jian-Jun Wang
University of Hong Kong · HKChinese University of Hong Kong · CNNanjing University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing interest in the role played by secretin in the central nervous system. Recent evidence suggests that this peptide is widely expressed in the brain but some areas, notably the cerebellum, show a prominent expression of the peptide and its specific receptor. In this article we summarize our current understanding of the expression pattern and action of secretin in the cerebellum. We discuss the findings supporting the endogenous release of this peptide from Purkinje neurons and its role as a retrograde messenger modulating GABAergic synaptic transmission via multiple mechanisms. In addition, we would like to propose other possible, but still to be confirmed, functions of secretin in the cerebellum..

Indexed as

AnimalsCerebellar DiseasesCerebellumGene ExpressionHumansModels, NeurologicalReceptors, Gastrointestinal HormoneReceptors, G-Protein-CoupledSecretinReceptors, Gastrointestinal HormoneReceptors, G-Protein-CoupledSecretinsecretin receptor

Identifiers

PMID16527763
OpenAlexW2165994315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.