ReviewCerebellum (London, England)2006
Nuclear Ca2+ signalling in cerebellar Purkinje neurons.
Review in Cerebellum (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Spatial transcriptomics analysis uncovers ER stress in MANF-deficient Purkinje cells underlying alcohol-induced cerebellar neurodegeneration in mice.Acta neuropathologica communications · 2025Article
- Functional Consequences of Calcium-Dependent Synapse-to-Nucleus Communication: Focus on Transcription-Dependent Metabolic Plasticity.Cold Spring Harbor perspectives in biology · 2020Review
- Neurotoxicity by synthetic androgen steroids: oxidative stress, apoptosis, and neuropathology: A review.Current neuropharmacology · 2015Review
- Article
- Nuclear Na+/K+-ATPase plays an active role in nucleoplasmic Ca2+ homeostasis.Journal of cell science · 2012Article
- Neuronal activity-regulated gene transcription: how are distant synaptic signals conveyed to the nucleus?F1000Research · 2012Review
- Calcium signaling in synapse-to-nucleus communication.Cold Spring Harbor perspectives in biology · 2011Review
- Anabolic androgenic steroids and intracellular calcium signaling: a mini review on mechanisms and physiological implications.Mini reviews in medicinal chemistry · 2011Review
- The large-conductance ion channels in the nuclear envelope of central neurons.Pflugers Archiv : European journal of physiology · 2010Article
- Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release.The Journal of biological chemistry · 2008Article
- The cerebellum, cerebellar disorders, and cerebellar research--two centuries of discoveries.Cerebellum (London, England) · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
An increase in nuclear Ca(2+) concentration may activate nuclear Ca(2+)-sensitive proteins and thereby regulate gene transcription. Ca(2+) can enter the nucleus from the cytoplasm either through nuclear pores or less certainly by release from the nuclear envelope. Recent studies indicate that the nuclear membrane of cerebellar Purkinje, but not granule neurons, contains multiple inositol 1,4,5-trisphosphate receptors (InsP(3)Rs) localized to the inner nuclear membrane. These data suggest that the nuclear envelope in some neurons is a Ca(2+) store specialized to release Ca(2+) directly into the nucleoplasm and thereby to amplify Ca(2+) signals entering the nucleus from the cytoplasm or to generate nuclear Ca(2+) transients on its own. Here we review current data on the mechanisms of regulation of Ca(2+) in the cell nucleus with particular emphasis on cerebellar Purkinje neurons.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.