Evidence map›Paper›PMID 16524540›Full record

ReviewCurrent cardiology reports2006

Imaging cardiac neuronal function and dysfunction.

Takahiro Higuchi, Markus Schwaiger

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Cardiac sympathetic imaging in heart failure: Is revival possible?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  2. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  3. Review
  4. Review
  5. Molecular Imaging of the Heart.Comprehensive Physiology · 2019
    Review
  6. PET/MR: Yet another Tesla?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Traditional and novel methods to assess and prevent chemotherapy-related cardiac dysfunction noninvasively.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Review
  12. Article
  13. Multimodality and nanoparticles in medical imaging.Dalton transactions (Cambridge, England : 2003) · 2011
    Article
  14. Molecular imaging targets of cardiac remodeling.Current cardiology reports · 2009
    Review
  15. Article
  16. Early imaging in heart failure: exploring novel molecular targets.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Takahiro HiguchiNuklearmedizinische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universität München, Ismaninger Strasse 22, 81675 München, Germany.
Markus Schwaiger
Klinikum rechts der Isar · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the importance of alterations of cardiac autonomic nerve function in the pathophysiology of heart diseases including heart failure, arrhythmia, ische-mic heart disease, and diabetes has been increasingly recognized. Several radiolabeled compounds have been synthesized for noninvasive imaging, including single photon emission CT and positron emission tomography (PET). The catecholamine analogue I-123 metaiodobenzylguanidine (MIBG) is the most commonly used tracer for mapping of myocardial presynaptic sympathetic innervation on a broad clinical basis. In addition, radiolabeled catecholamines and catecholamine analogues are available for PET imaging, which allows absolute quantification and tracer kinetics modeling. Postsynaptic receptor PET imaging added new insights into mechanisms of heart disease. These advanced imaging techniques provide noninvasive, repeatable in vivo information of autonomic nerve function in the human heart and are promising for providing profound insights into molecular pathophysiology, monitoring of treatment, and determination of individual outcome.

Indexed as

Arrhythmias, CardiacCoronary CirculationDiabetic NeuropathiesHeartHeart DiseasesHeart FailureHumansMyocardial IschemiaMyocardiumParasympathetic Nervous SystemPositron-Emission TomographySympathetic Nervous SystemTomography, Emission-Computed, Single-Photon

Identifiers

PMID16524540
OpenAlexW2010916274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.