ArticleNano letters2006
Detection of DNA hybridization using the near-infrared band-gap fluorescence of single-walled carbon nanotubes.
Article in Nano letters, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 309 citations in OpenAlex.
- Antibody-conjugated species-sorted single-walled carbon nanotubes for multiplexed cytokine sensing.Communications materials · 2026Article
- Rational Design of Optical Single-Walled Carbon Nanotube-Based Nanosensors with Biological Recognition Elements.Advanced sensor research · 2026Article
- Multiplexed Molecularly-Specific SWCNT Cytokine Sensing is Enabled and Enhanced by Amine-Functionalized DNA Aqueous Two-Phase Extraction.bioRxiv : the preprint server for biology · 2025Article
- Highly-Selective Harvesting of (6,4) SWCNTs Using the Aqueous Two-Phase Extraction Method and Nonionic Surfactants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Bioengineering a glucose oxidase nanosensor for near-infrared continuous glucose monitoring.Nanoscale advances · 2022Article
- Biosensing with Fluorescent Carbon Nanotubes.Angewandte Chemie (International ed. in English) · 2022Review
- Functionalization of Nanomaterials for Skin Cancer Theranostics.Frontiers in bioengineering and biotechnology · 2022Review
- Stable Near-Infrared Photoluminescence of Single-Walled Carbon Nanotubes Dispersed Using a Coconut-Based Natural Detergent.ACS omega · 2021Article
- Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments.Angewandte Chemie (International ed. in English) · 2020Article
- Corona Exchange Dynamics on Carbon Nanotubes by Multiplexed Fluorescence Monitoring.Journal of the American Chemical Society · 2020Article
- Synthetic molecular recognition nanosensor paint for microalbuminuria.Nature communications · 2019Article
- Non-covalent Methods of Engineering Optical Sensors Based on Single-Walled Carbon Nanotubes.Frontiers in chemistry · 2019Review
- A fundamental study of photoluminescence modulation from DNA-wrapped single-walled carbon nanotubes.European biophysics journal : EBJ · 2018Article
- Review
- Carbon nanotubes in microfluidic lab-on-a-chip technology: current trends and future perspectives.Microfluidics and nanofluidics · 2017Article
- Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes.Journal of visualized experiments : JoVE · 2017Article
- Nanomaterial-based sensors for the detection of biological threat agents.Materials today (Kidlington, England) · 2016Review
- Physisorption of DNA molecules on chemically modified single-walled carbon nanotubes with and without sonication.European biophysics journal : EBJ · 2016Article
- Biosensing with Förster Resonance Energy Transfer Coupling between Fluorophores and Nanocarbon Allotropes.Sensors (Basel, Switzerland) · 2015Review
- Ambient solid-state mechano-chemical reactions between functionalized carbon nanotubes.Nature communications · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We demonstrate the optical detection of DNA hybridization on the surface of solution suspended single-walled carbon nanotubes (SWNTs) through a SWNT band gap fluorescence modulation. Hybridization of a 24-mer oligonucleotide sequence with its complement produces a hypsochromic shift of 2 meV, with a detection sensitivity of 6 nM. The energy shift is modeled by correlating the surface coverage of DNA on SWNT to the exciton binding energy, yielding an estimated initial fractional coverage of 0.25 and a final coverage of 0.5. Hybridization on the nanotube surface is confirmed using Forster resonance energy transfer of fluorophore-labeled DNA oligonucleotides. This detection is enabled through a new technique to suspend SWNTs using adsorption of single-stranded DNA and subsequent removal of free DNA from solution. While the kinetics of free DNA hybridization are relatively fast (<10 min), the kinetics of the process on SWNTs are slower under comparable conditions, reaching steady state after 13 h at 25 degrees C. A second-order kinetic model yields a rate constant of k = 4.33 x 10(5) (M h)(-1). This optical, selective detection of specific DNA sequences may have applications in the life sciences and medicine as in vitro or in vivo detectors of oligonucleotides.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.