ReviewThe Canadian journal of cardiology2006
Antihypertensive medications and blood sugar: theories and implications.
Review in The Canadian journal of cardiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Systolic Blood Pressure and Risk of Type 2 Diabetes: A Mendelian Randomization Study.Diabetes · 2017Pooled it
- Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes Remission Clinical Trial (DiRECT).Diabetologia · 2021Trial
- Diabetes in residential aged care: Pharmacological management and concordance with clinical guidelines.Australasian journal on ageing · 2024Article
- Glucose Alterations, Insulin Resistance, Arterial Hypertension, and Renin are Strictly Associated in Pediatric Obesity.Journal of the Endocrine Society · 2023Article
- Association of antihypertensive drugs with fracture and bone mineral density: A comprehensive drug-target Mendelian randomization study.Frontiers in endocrinology · 2023Article
- Article
- Metabolic syndrome and its associated factors in Ethiopia: A systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2021Review
- Antihypertensive agents: a long way to safe drug prescribing in children.Pediatric nephrology (Berlin, Germany) · 2020Review
- Hypertension, but not body mass index, is predictive of increased pancreatic lipid content and islet dysfunction.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020Article
- Alpha Adducin (ADD1) Gene Polymorphism and New Onset of Diabetes Under the Influence of Selective Antihypertensive Therapy in Essential Hypertension.Current hypertension reviews · 2019Article
- Contribution and interaction of the low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and triglyceride to diabetes in hypertensive patients: A cross-sectional study.Journal of diabetes investigation · 2019Article
- Article
- Effects of Azilsartan, Aliskiren or their Combination on High Fat Diet-induced Non-alcoholic Liver Disease Model in Rats.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2017Article
- Observational
- Association between glycemic control and antidiabetic drugs in type 2 diabetes mellitus patients with cardiovascular complications.Drug design, development and therapy · 2015Article
- Article
- Severe diltiazem poisoning treated with hyperinsulinaemia-euglycaemia and lipid emulsion.Case reports in critical care · 2013Article
- Bench-to-bedside review: hyperinsulinaemia/euglycaemia therapy in the management of overdose of calcium-channel blockers.Critical care (London, England) · 2006Review
- Effect of losartan and atenolol on insulin sensitivity in nondiabetic hypertensive patients.Journal of pharmacology & pharmacotherapeuticsArticle
- Cardiovascular Safety of Oral Antidiabetic Medications: Need of the Hour.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased rates of diabetes have been reported with thiazide diuretics and beta-blockers, but not with angiotensin-converting enzyme inhibitors, angiotensin receptor blockers or calcium channel blockers. These observations are important because significant glycemic effects of drugs may be a source of accelerated cardiovascular risk that is not detectable during restricted clinical trial follow-up periods. The extent to which diabetes is affected by these medications remains unclear, as is the precise mechanism by which diabetes is promoted. However, several plausible theories are presented herein. Although drug-induced diabetes has been a concern for several years, not enough information is available to influence prescribing for the majority of patients. The number one priority should be controlling blood pressure in a timely manner.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.