ReviewThe Canadian journal of cardiology2006
Is South Asian ethnicity an independent cardiovascular risk factor?
Review in The Canadian journal of cardiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 7 syntheses or guidelines pooled it, 165 citations in OpenAlex.
- Ethnic disparities in mortality from acute coronary syndromes: a systematic review and meta-analysis.Open heart · 2026Pooled it
- South Asian Experiences of Palliative and End-of-Life Care Provision in the UK: A Systematic Literature Review and Thematic Synthesis.Journal of palliative care · 2026Pooled it
- Exploring associations between estrogen and gene candidates identified by coronary artery disease genome-wide association studies.Frontiers in cardiovascular medicine · 2025Pooled it
- Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis.BMJ open diabetes research & care · 2024Pooled it
- Objective measurement of physical activity and sedentary behavior among South Asian adults: A systematic review.PloS one · 2020Pooled it
- Examining sedentary time as a risk factor for cardiometabolic diseases and their markers in South Asian adults: a systematic review.International journal of public health · 2017Pooled it
- Physical activity patterns among South-Asian adults: a systematic review.The international journal of behavioral nutrition and physical activity · 2013Pooled it
- Trial
- Intervention effects on physical activity and insulin levels in men of Pakistani origin living in Oslo: a randomised controlled trial.Journal of immigrant and minority health · 2013Trial
- Metal and metal mixture biomarkers across three U.S. cohorts: MASALA, MESA-LA, and Strong Heart Family Study.Journal of exposure science & environmental epidemiology · 2026Article
- The Canadian multi-ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Observational
- Barriers to hypertension management in a developing country: a qualitative study among patients with hypertension at the National Hospital of Sri Lanka.BMC public health · 2026Article
- Article
- Effects of a single bout of low-intensity isometric or moderate-intensity aerobic exercise on postexercise hypotension in adults of African and south-Asian descent: a randomized controlled crossover trial.Frontiers in rehabilitation sciences · 2026Article
- Real-world assessment of low-density lipoprotein cholesterol goal, disease burden and financial burden among patients with atherosclerotic cardiovascular disease in Singapore-A single-centre retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Knowledge, attitudes, practices, and perceived barriers of physicians in promoting physical activity in Urban Odisha, India.Journal of family medicine and primary care · 2025Article
- Addressing myocardial infarction in South-Asian populations: risk factors and machine learning approaches.NPJ cardiovascular health · 2025Review
- A lipidomic dataset for epidemiological studies of acute myocardial infarction.Data in brief · 2024Article
- Adult mortality from non-communicable diseases in Fiji's major ethnic groups 2013-17.Global epidemiology · 2024Article
- Primary prevention of cardiovascular diseases among women in a South Asian population: a descriptive study of modifiable risk factors.BMJ open · 2024Observational
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
People of South Asian origin constitute a large, visible minority in Canada and are known to be at heightened risk for premature coronary artery disease. Conventional risk factors clearly confer risk in South Asians but do not adequately explain their excess risk compared with other populations. Rates of smoking, hypertension and levels of low density lipoprotein-cholesterol tend to be similar or lower in South Asians, although diabetes is more prevalent. Recent studies have suggested that the metabolic syndrome and abdominal obesity may play a causative role in both the prevalence of diabetes and the premature atherosclerosis noted in South Asians. It is possible that genetically susceptible individuals develop abdominal obesity and insulin resistance when exposed to a toxic environment of reduced energy expenditure and increased caloric consumption. This pattern is increasingly noted in parallel with urbanization, suggesting that the increased cardiovascular risk in South Asians may be preventable through lifestyle interventions and the judicious use of medicines to attain optimal levels of blood pressure, lipids and glucose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.