ArticleJournal of clinical microbiology2006
Detection of new methicillin-resistant Staphylococcus aureus clones containing the toxic shock syndrome toxin 1 gene responsible for hospital- and community-acquired infections in France.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 133 citations in OpenAlex.
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- Whole-Genome Investigation of Zoonotic Transmission of Livestock-Associated Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Markers of epidemiological success of methicillin-resistant Staphylococcus aureus isolates in European populations.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023Article
- Comparison of genotyping methods and toxin gene profiles of Staphylococcus aureus isolates from clinical specimens.Genetics and molecular biology · 2023Article
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- Pathogenicity and Molecular Characterization ofBioMed research international · 2021Article
- Review
- Carriage of the Toxic Shock Syndrome Toxin Gene by Contemporary Community-Associated Staphylococcus aureus Isolates.Journal of the Pediatric Infectious Diseases Society · 2019Article
- Emergence of novel methicillin-resistantInfection and drug resistance · 2019Article
- Distribution of the Most PrevalentFrontiers in microbiology · 2018Review
- Routine Whole-Genome Sequencing for Outbreak Investigations ofFrontiers in microbiology · 2018Article
- The TIR Homologue Lies near Resistance Genes in Staphylococcus aureus, Coupling Modulation of Virulence and Antimicrobial Susceptibility.PLoS pathogens · 2017Article
- Molecular typing, virulence traits and antimicrobial resistance of diabetic foot staphylococci.Journal of biomedical science · 2016Article
- Distribution of tsst-1 and mecA Genes in Staphylococcus aureus Isolated From Clinical Specimens.Jundishapur journal of microbiology · 2016Article
- The rise of staphylococcal super antigens in psoriatic patients: a case-control study.Jundishapur journal of microbiology · 2014Article
- Identification of bacterial antigens and super antigens in synovial fluid of patients with arthritis: a cross sectional study.Medical journal of the Islamic Republic of Iran · 2013Article
- Current concepts on the virulence mechanisms of meticillin-resistant Staphylococcus aureus.Journal of medical microbiology · 2012Review
- Antibacterial resistance, genes encoding toxins and genetic background among Staphylococcus aureus isolated from community-acquired skin and soft tissue infections in France: a national prospective survey.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) clones harboring the toxic shock syndrome toxin 1 (tst) gene have been detected in France and in Switzerland since 2002. During a passive survey conducted between 2002 and 2003, we collected 103 tst-positive S. aureus isolates from 42 towns in France, of which 27 were resistant to methicillin. The tst-positive MRSA belonged to two clones: a major clone comprising 25 isolates of sequence type (ST) 5 and agr group 2 and a minor clone comprising two isolates of ST30 and agr3. The tst-positive MRSA clones were associated with both hospital-acquired (12 cases) and community-acquired (8 cases) infections. The MRSA clones were mainly isolated from children (overall median age, 3 years). They caused a variety of clinical syndromes, including toxic shock syndrome and suppurative infections. Both clones were found to harbor a type IV staphylococcal chromosomal cassette mec (SCCmec) and to have similar antibiotic resistance profiles (usually resistant to oxacillin, kanamycin, and tobramycin and with intermediate resistance to fusidic acid). The origin of these clones is unclear. The tst-positive agr2 MRSA clone has the same sequence type (ST5) of two pandemic nosocomial MRSA clones, namely, the Pediatric clone and the New York/Japan clone. These findings suggest that all these clones are phylogenetically related. The pulsotype of the tst-positive MRSA clones differed from that of methicillin-sensitive S. aureus (MSSA) clones by a single band involving the SCCmec element. These findings suggest that the tst-positive MRSA clones may have emerged from their respective MSSA counterparts.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.