ArticleJournal of clinical microbiology2006
Single-nucleotide repeat analysis for subtyping Bacillus anthracis isolates.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Genetic diversity of Bacillus anthracis Ames lineage strains in China.BMC infectious diseases · 2020Article
- Epidemiological Investigation and Etiological Analysis of a Cutaneous Anthrax Epidemic Caused by Butchering Sick Cattle in Guizhou, China.Frontiers in public health · 2020Article
- Genetic source tracking of an anthrax outbreak in Shaanxi province, China.Infectious diseases of poverty · 2017Article
- Phylogenetic Characteristics of Anthrax Outbreaks in Liaoning Province, China, 2001-2015.PloS one · 2016Article
- Spatio-temporal patterns of an anthrax outbreak in white-tailed deer, Odocoileus virginanus, and associated genetic diversity of Bacillus anthracis.BMC ecology · 2015Article
- Microevolution of Anthrax from a Young Ancestor (M.A.Y.A.) Suggests a Soil-Borne Life Cycle of Bacillus anthracis.PloS one · 2015Article
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- Article
- Improved short-sequence-repeat genotyping of Mycobacterium avium subsp. paratuberculosis by using matrix-assisted laser desorption ionization-time of flight mass spectrometry.Applied and environmental microbiology · 2014Article
- Genetic diversity of Korean Bacillus anthracis isolates from soil evaluated with a single nucleotide repeat analysis.Journal of veterinary science · 2013Article
- Genetic populations of Bacillus anthracis isolates from Korea.Journal of veterinary science · 2012Article
- Comparative genomics and transcriptomics of trait-gene association.BMC genomics · 2012Article
- Genetic diversity among Bacillus anthracis soil isolates at fine geographic scales.Applied and environmental microbiology · 2012Article
- Distribution and molecular evolution of bacillus anthracis genotypes in Namibia.PLoS neglected tropical diseases · 2012Article
- Characterization of genetic diversity of Bacillus anthracis in France by using high-resolution melting assays and multilocus variable-number tandem-repeat analysis.Journal of clinical microbiology · 2011Article
- The phenotypic and genotypic characterization of Bacillus anthracis isolates from Iran.Tropical animal health and production · 2011Article
- SNR analysis: molecular investigation of an anthrax epidemic.BMC veterinary research · 2010Article
- Conservation in the face of diversity: multistrain analysis of an intracellular bacterium.BMC genomics · 2009Article
- Occurrence and genetic diversity of Bacillus anthracis strains isolated in an active wool-cleaning factory.Applied and environmental microbiology · 2008Article
- Multilocus sequence typing of Lactobacillus casei reveals a clonal population structure with low levels of homologous recombination.Applied and environmental microbiology · 2007Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single-nucleotide repeats (SNRs) are variable-number tandem repeats that display very high mutation rates. In an outbreak situation, the use of a marker system that exploits regions with very high mutation rates, such as SNRs, allows the differentiation of isolates with extremely low levels of genetic diversity. This report describes the identification and analysis of SNR loci of Bacillus anthracis. SNR loci were selected in silico, and the loci with the highest diversity were used to design and test locus-specific primers against a number of B. anthracis strains with the same multilocus variable-number tandem repeat analysis (MLVA) genotype. SNR markers that allowed strains with the same MLVA genotype to be differentiated from each other were identified. The resulting SNR marker system can be used as a molecular epidemiological tool in a natural outbreak or bioterrorism event, offering the best chance of distinguishing very closely related isolates.
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